Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185817 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL4181297 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL31538574 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL4333252 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL4187652 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL5371520 | 0.78 | KDM4E (0.66) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL4190437 | 0.75 | LMNA (0.61) | ALDH1A1KDM4EL3MBTL1TSHRRAB9A | |
| SCHEMBL31531227 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL31538652 | 0.74 | KDM4E (0.60) | ALDH1A1KDM4EL3MBTL1HSD17B10TSHR | |
| SCHEMBL4178799 | 0.74 | NPSR1 (0.47) | ALDH1A1KDM4EKMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | claimed |
| WO-2009048274-A2 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES SUBSTITUTED WITH AMIDE, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-16 | — | — | WO | disclosed |