Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27867872 | 0.92 | MLNR (0.48) | MLNRMAPTCYP1A2CYP2A6LMNA | |
| Formic Acid Methyl Ester SCHEMBL28104574 | 0.88 | MLNR (0.45) | MLNRMAPTCYP1A2CYP2A6LMNA | |
| SCHEMBL4203432 | 0.86 | MLNR (0.52) | MLNRCYP1A2CYP2A6LMNASMN1; SMN2 | |
| SCHEMBL28389504 | 0.81 | MLNR (0.57) | MLNRLMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL27450675 | 0.80 | CYP1A2 (0.54) | MLNRCYP1A2CYP2A6LMNACA1 | |
| SCHEMBL294031 | 0.79 | CYP1A2 (0.52) | MLNRCYP1A2CYP2A6LMNACA1 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.78 | TSHR (0.68) | MAPTLMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL2374771 | 0.77 | CYP1A2 (0.50) | MLNRCYP1A2CYP2A6LMNACA1 | |
| SCHEMBL1764709 | 0.77 | CA1 (0.57) | MLNRCYP1A2CYP2A6LMNACA1 | |
| SCHEMBL12230567 | 0.77 | CYP1A2 (0.50) | MLNRCYP1A2CYP2A6LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | claimed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | disclosed |
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2008157216-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | HTR6, HTR2B, HTR3B | MLNR 65/4885MAPT 4847/4885CYP1A2 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.