Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425330 | 0.96 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL2420821 | 0.90 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL7439831 | 0.88 | MEN1 (0.43) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL4968679 | 0.88 | MAPK9 (0.44) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL1518735 | 0.86 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2423593 | 0.85 | KMT2A (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL2424569 | 0.84 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2418429 | 0.83 | MEN1 (0.46) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL5565272 | 0.83 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL1518747 | 0.83 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |