Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425330 | 0.91 | MAPK9 (0.51) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL4970353 | 0.89 | MEN1 (0.39) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL2419191 | 0.88 | MAPK9 (0.52) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL4197299 | 0.88 | MAPK9 (0.47) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL4198065 | 0.86 | MEN1 (0.37) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL2423593 | 0.81 | KMT2A (0.48) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL1518747 | 0.80 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL2424569 | 0.80 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL2418429 | 0.79 | MEN1 (0.46) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL5565272 | 0.79 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |