Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194159 | 0.90 | CCR5 (0.64) | CCR5KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL13853344 | 0.89 | CCR5 (0.62) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL4189869 | 0.88 | CCR5 (0.61) | CCR5KCNH2 | |
| SCHEMBL4205859 | 0.86 | CCR5 (0.55) | CCR5KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL4198186 | 0.86 | CCR5 (0.59) | CCR5KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL4187589 | 0.84 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL13853349 | 0.80 | CCR5 (0.64) | CCR5KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL4201880 | 0.79 | CCR5 (0.63) | CCR5KCNH2CHRM2 | |
| SCHEMBL4197482 | 0.78 | CCR5 (0.58) | CCR5KCNH2 | |
| SCHEMBL12202511 | 0.77 | CCR5 (0.65) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CCR2 | CCR5 1/4885KCNH2 2799/4885CHRM2 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.