SCHEMBL4198178

SCHEMBL4198178

CC(=COc1ccc2ccccc2c1)C(=O)OCCCOc1ccc(-c2ccccc2OCCCOC(=O)C(C)=COc2ccc3ccccc3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.42
KDM4E B2RXH2 6/20 0.39
PPARA Q07869 4/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
PAX8 Q06710 1/20 0.38
PPARG P37231 3/20 0.38
PPARD Q03181 3/20 0.38
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC1 Q13547 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4196022 0.93 KDM4E (0.38) KDM4EPPARAMEN1KMT2ALMNA
SCHEMBL4198432 0.90 PPARA (0.43) KDM4EPPARAPPARGPPARDALDH1A1
SCHEMBL4204704 0.89 KDM4E (0.40) KDM4EPPARAMEN1KMT2ALMNA
SCHEMBL4193372 0.89 PPARA (0.46) KDM4EPPARAMAPTPPARGPPARD
SCHEMBL4188678 0.89 FFAR4 (0.46) FFAR4KDM4EPPARAMEN1KMT2A
SCHEMBL4202648 0.88 FFAR4 (0.45) FFAR4KDM4EPPARALMNAPPARG
SCHEMBL4186160 0.87 FFAR4 (0.47) FFAR4KDM4EMEN1KMT2AALDH1A1
SCHEMBL4191185 0.87 KCNA3 (0.43) FFAR4KDM4EPPARAMEN1KMT2A
SCHEMBL4198746 0.87 FFAR4 (0.53) FFAR4KDM4EPPARAPPARGPPARD
SCHEMBL4197503 0.84 FFAR4 (0.48) FFAR4KDM4EPPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 FFAR4 1889/4885KDM4E 270/4885PPARA 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.