SCHEMBL4204704

SCHEMBL4204704

CC(=COc1ccc2ccccc2c1)C(=O)OCCCOc1ccccc1OCCCOC(=O)C(C)=COc1ccc2ccccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PTPN7 P35236 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
PPARA Q07869 3/20 0.39
HDAC1 Q13547 2/20 0.39
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
RAB9A P51151 1/20 0.38
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RECQL P46063 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4196022 0.94 KDM4E (0.38) KDM4EALDH1A1PTPN7MEN1KMT2A
SCHEMBL4193372 0.93 PPARA (0.46) KDM4EALDH1A1PTPN7PPARAHDAC1
SCHEMBL4198178 0.89 FFAR4 (0.42) KDM4EALDH1A1MEN1KMT2APPARA
SCHEMBL4190895 0.89 MEN1 (0.44) KDM4EALDH1A1MEN1KMT2ARAB9A
SCHEMBL4198432 0.89 PPARA (0.43) KDM4EALDH1A1PTPN7PPARAHDAC1
SCHEMBL4190462 0.89 KDM4E (0.44) KDM4EALDH1A1PTPN7MEN1KMT2A
SCHEMBL4198605 0.85 KDM4E (0.36) KDM4EALDH1A1PTPN7MEN1KMT2A
SCHEMBL4204186 0.84 PPARG (0.42) KDM4EPPARAHDAC1PPARGPPARD
SCHEMBL4198157 0.83 FFAR4 (0.41) MEN1KMT2AHDAC1PPARGPPARD
SCHEMBL12851507 0.82 GAA (0.44) KDM4EPTPN7MEN1KMT2APPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 KDM4E 270/4885ALDH1A1 568/4885PTPN7 4180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.