Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 1.00 |
| ▸ | HTR1B | P28222 | 8/20 | 1.00 |
| ▸ | HTR1D | P28221 | 7/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 1.00 |
| ▸ | HTR7 | P34969 | 2/20 | 1.00 |
| ▸ | HTR6 | P50406 | 2/20 | 1.00 |
| ▸ | HTR4 | Q13639 | 2/20 | 1.00 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 0.97 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.97 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.97 |
| ▸ | HTR2B | P41595 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Methoxytryptamine SCHEMBL29390103 | 1.00 | HTR1A (1.00) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL26617456 | 0.98 | HTR1A (0.97) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL130877 | 0.98 | HTR1A (0.97) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL1322980 | 0.98 | NPSR1 (1.00) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL31109114 | 0.98 | NPSR1 (1.00) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL28309973 | 0.96 | HTR1A (0.91) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL28681558 | 0.96 | HTR1A (0.91) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL27863884 | 0.94 | HTR1A (0.89) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL27863882 | 0.93 | HTR1A (0.86) | HTR1AHTR1BHTR1DHTR2ACYP1A2 | |
| 5-Methoxytryptamine SCHEMBL30812526 | 0.92 | HTR1A (0.84) | HTR1AHTR1BHTR1DHTR2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2656 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595497-B2 | Processes for the production of tryptamines | COMPASS PATHFINDER LIMITED (GB) | 2026-04-07 | — | — | US | claimed |
| US-20250275935-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH DEMENTIA DUE TO ALZHEIMER'S DISEASE WITH A COMBINATION OF THC AND MELATONIN | IGC PHARMA IP, LLC (US) | 2025-09-04 | — | — | US | claimed |
| CN-120195409-A | Composition for diagnosing sepsis and medicament for sepsis preventive treatment | 北京大学第三医院（北京大学第三临床医学院） | 2025-06-24 | — | — | CN | claimed |
| CN-120019812-A | Artificial toad venom composition and application thereof | 南京中医药大学 | 2025-05-20 | — | — | CN | claimed |
| CN-118897028-B | Biomarker for predicting gout attack risk and application thereof | 查理高特(青岛)健康科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-115974756-B | Melatonin and purification method of crystallization mother liquor thereof | 福建科宏生物工程股份有限公司 | 2025-01-10 | — | — | CN | claimed |
| US-20250002506-A1 | IMPROVED PROCESS FOR THE PREPARATION OF LURBINECTEDIN AND ITS MORPHS THEREOF | RK PHARMA INC. (US) | 2025-01-02 | — | — | US | claimed |
| CN-118955501-A | Beta-carbazoline derivative and synthetic method and application thereof | 新乡医学院 | 2024-11-15 | — | — | CN | claimed |
| CN-114230507-B | Preparation method of 5-methoxy tryptamine | 阜阳欣奕华制药科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118897028-A | Biomarker for predicting gout attack risk and application thereof | 查理高特(青岛)健康科技有限公司 | 2024-11-05 | — | — | CN | claimed |
| EP-0197389-B1 | PREPARATION OF MEXAMINE | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1988-11-09 | — | — | EP | claimed |
| US-4772726-A | Preparation of melatonine and mexamine | NESTEC S. A. (CH) | 1988-09-20 | — | — | US | claimed |
| US-4746674-A | Melatonin compositions and uses thereof | CELLENA (CELL ENGINEERING) AG (CH) | 1988-05-24 | — | — | US | claimed |
| EP-0246910-A2 | Coated veterinary implants | Hoechst Veterinär GmbH (DE) | 1987-11-25 | — | — | EP | claimed |
| EP-0229131-A1 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGENEERING) A.G. (CH) | 1987-07-22 | — | — | EP | claimed |
| WO-1987000432-A2 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGINEERING) A.G. (CH) | 1987-01-29 | — | — | WO | claimed |
| EP-0197389-A2 | Preparation of mexamine | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1986-12-03 | — | — | EP | claimed |
| EP-0149405-A2 | Antibodies capable of specifically recognizing haptenic groups, their preparation and application, and antigens for the preparation of these antibodies | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1985-07-24 | — | — | EP | claimed |
| EP-0130303-A1 | Process for separation of serotonine | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1985-01-09 | — | — | EP | claimed |
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |