Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420635 | 0.81 | LMNA (0.44) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL2984488 | 0.78 | QPCT (0.37) | MEN1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL13297796 | 0.77 | EHMT2 (0.49) | EHMT2ELANEMEN1KMT2AF2 | |
| SCHEMBL6553143 | 0.77 | MEN1 (0.49) | EHMT2ELANEMEN1KMT2AF2 | |
| SCHEMBL31173351 | 0.76 | EHMT2 (0.45) | EHMT2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6551986 | 0.76 | HSD11B1 (0.48) | EHMT2ELANEMEN1KMT2AF2 | |
| SCHEMBL11660768 | 0.75 | MEN1 (0.66) | MEN1KMT2AHPGDALDH1A1TP53 | |
| SCHEMBL3627524 | 0.73 | EHMT2 (0.45) | EHMT2ELANEMEN1KMT2AF2 | |
| SCHEMBL9631715 | 0.73 | EHMT2 (0.45) | EHMT2ELANEMEN1KMT2AF2 | |
| SCHEMBL7498416 | 0.73 | EHMT2 (0.45) | EHMT2ELANEMEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005364-A1 | Azole Derivatives With Antimuscarinic Activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2009-01-01 | — | — | US | disclosed |
| EP-1828163-A2 | AZOLE DERIVATIVES WITH ANTIMUSCARINIC ACTIVITY | CHIESI FARMACEUTICI S.p.A. (IT) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066924-A2 | AZOLE DERIVATIVES WITH ANTIMUSCARINIC ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005364-A1 | Azole Derivatives With Antimuscarinic Activity | CHRM2, CHRM3, CHRM1 | EHMT2 2308/4885ELANE 2115/4885MEN1 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.