SCHEMBL4198617

SCHEMBL4198617

CC(=COc1ccccc1)C(=O)OCCCOc1c(C)cc(-c2cc(C)c(OCCCOC(=O)C(C)=COc3ccccc3)c(C)c2)cc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
FFAR4 Q5NUL3 3/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
PPARD Q03181 1/20 0.36
CYP3A4 P08684 1/20 0.35
KCNH2 Q12809 1/20 0.35
CACNA1C Q13936 1/20 0.35
SCN5A Q14524 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 2/20 0.35
APP P05067 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4194743 0.96 KDM4E (0.37) FFAR4KDM4EALDH1A1PPARGPPARA
SCHEMBL4197215 0.94 PPARG (0.43) MEN1KMT2AATMFFAR4PPARG
SCHEMBL4202675 0.92 FFAR4 (0.39) L3MBTL1FFAR4PPARGPPARAPPARD
SCHEMBL4198605 0.89 KDM4E (0.36) MEN1KMT2AFFAR4KDM4EALDH1A1
SCHEMBL4198640 0.89 PPARG (0.47) FFAR4PPARGPPARAPPARDTDP1
SCHEMBL4190846 0.85 KDM4E (0.40) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL4197206 0.83 HDAC1 (0.46) L3MBTL1FFAR4PPARGPPARAPPARD
SCHEMBL4202738 0.82 ALDH1A1 (0.40) KMT2AKDM4EALDH1A1TDP1
SCHEMBL4184738 0.81 PPARD (0.46) L3MBTL1FFAR4KDM4EPPARGPPARA
SCHEMBL4197471 0.80 PPARG (0.41) L3MBTL1PPARGPPARAPPARDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 MEN1 744/4885KMT2A 266/4885ATM 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.