Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945143 | 0.92 | RAB9A (0.49) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL4211391 | 0.91 | RAB9A (0.46) | RAB9ANPC1TRPV1CCR2MEN1 | |
| SCHEMBL3944227 | 0.90 | DGAT1 (0.40) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL4202348 | 0.88 | MAPT (0.52) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL4208314 | 0.85 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4206617 | 0.84 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4028416 | 0.84 | RAB9A (0.43) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL3941454 | 0.84 | RAB9A (0.58) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL3942490 | 0.84 | RAB9A (0.58) | RAB9ANPC1ACKR3MEN1KMT2A | |
| SCHEMBL3944015 | 0.84 | RAB9A (0.58) | RAB9ANPC1ACKR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |