Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211391 | 0.91 | RAB9A (0.46) | RAB9ANPC1KMT2AMEN1HAT1 | |
| SCHEMBL4199502 | 0.90 | RAB9A (0.43) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL3945143 | 0.90 | RAB9A (0.49) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3945345 | 0.89 | ALDH1A1 (0.42) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL3943464 | 0.89 | ALDH1A1 (0.44) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL3943864 | 0.88 | ALDH1A1 (0.38) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL3940683 | 0.88 | MAPT (0.50) | DGAT1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL3941054 | 0.85 | MAPT (0.49) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3941048 | 0.85 | MAPT (0.49) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4206065 | 0.84 | ALDH1A1 (0.51) | RAB9ANPC1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |