SCHEMBL4199715

SCHEMBL4199715

CC(CC1CCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc(NS(=O)(=O)c2cn(C)cn2)cn1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
PIK3CG P48736 8/20 0.42
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.39
GLO1 Q04760 1/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
IRS1 P35568 1/20 0.36
GAB1 Q13480 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP1 P09874 1/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197418 0.93 KDM4E (0.51) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4195588 0.92 KDM4E (0.52) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4193042 0.91 KDM4E (0.45) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4194953 0.90 KDM4E (0.46) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4198102 0.88 KDM4E (0.47) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4197632 0.87 KDM4E (0.39) KDM4ELMNAALDH1A1SMN1; SMN2PKM
SCHEMBL4193193 0.87 KDM4E (0.44) KDM4EPIK3CGGAALMNAGLO1
SCHEMBL4200124 0.86 PIK3CG (0.45) KDM4EPIK3CGGAAKMT2A
SCHEMBL4197319 0.84 KDM4E (0.41) KDM4EGAALMNATSHRALDH1A1
SCHEMBL14343959 0.83 KDM4E (0.34) KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KDM4E 3328/4885PIK3CG 1756/4885GAA 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.