SCHEMBL4200124

SCHEMBL4200124

COc1cc(NS(=O)(=O)c2cn(C)cn2)ccc1S(=O)(=O)Nc1ccccc1CNC(C)CC1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 13/20 0.45
HTR6 P50406 1/20 0.43
KDM4E B2RXH2 1/20 0.41
PIK3CD O00329 1/20 0.38
GAA P10253 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SSTR5 P35346 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197418 0.88 KDM4E (0.51) PIK3CGKDM4EGAAKMT2A
SCHEMBL4198102 0.87 KDM4E (0.47) PIK3CGKDM4EGAAKMT2A
SCHEMBL4195588 0.87 KDM4E (0.52) PIK3CGKDM4EGAAKMT2A
SCHEMBL4193042 0.86 KDM4E (0.45) PIK3CGKDM4EGAAKMT2A
SCHEMBL4193193 0.86 KDM4E (0.44) PIK3CGKDM4EGAAMEN1KMT2A
SCHEMBL4199715 0.86 KDM4E (0.45) PIK3CGKDM4EGAAKMT2A
SCHEMBL4194953 0.85 KDM4E (0.46) PIK3CGKDM4EGAAKMT2A
SCHEMBL4201848 0.85 SMN1; SMN2 (0.42) KDM4EKMT2A
SCHEMBL4185858 0.82 ALDH1A1 (0.44) KDM4EMEN1KMT2A
SCHEMBL4197884 0.82 ALDH1A1 (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 PIK3CG 1756/4885HTR6 3438/4885KDM4E 3328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.