SCHEMBL4199764

SCHEMBL4199764

CCCCCCc1ccc(C(=O)ON(CC)CC)c(O)c1C(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.46
MCL1 Q07820 6/20 0.46
BCL2L1 Q07817 5/20 0.46
BAK1 Q16611 5/20 0.46
PPARA Q07869 3/20 0.46
KAT8 Q9H7Z6 3/20 0.46
PPARG P37231 2/20 0.46
SAE1 Q9UBE0 2/20 0.46
EP300 Q09472 2/20 0.46
KAT5 Q92993 2/20 0.46
KAT2A Q92830 1/20 0.46
KAT2B Q92831 1/20 0.46
F7 P08709 3/20 0.41
F3 P13726 3/20 0.41
MMP2 P08253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
ECE1 P42892 1/20 0.41
SGMS1 Q86VZ5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995527 0.82 BID (0.43) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL28524989 0.81 ALOX5 (0.50) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL17361143 0.79 TSHR (0.49) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL19611499 0.79 KAT8 (0.40) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL27842727 0.79 KAT8 (0.40) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL28790813 0.78 PTPN1 (0.41) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL27652898 0.78 BID (0.48) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL4610010 0.78 PPARA (0.47) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL27797054 0.77 BID (0.50) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL27513559 0.77 BID (0.51) BIDMCL1BCL2L1BAK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3265051-B1 AQUEOUS SUN-RELATED COSMETIC COMPOSITION FREE OF SURFACTANTS NAOS LES LABORATOIRES (FR) 2020-06-24 EP claimed
EP-3236913-B1 COSMETIC SUNSCREEN COMPOSITION GALDERMA SA (CH) 2020-04-01 EP claimed
CN-112118825-B Topical compositions 帝斯曼知识产权资产管理有限公司 2023-03-31 CN disclosed
CN-112165975-A Topical compositions 帝斯曼知识产权资产管理有限公司 2021-01-01 CN disclosed
CN-112118825-A Topical compositions 帝斯曼知识产权资产管理有限公司 2020-12-22 CN disclosed
EP-3636246-A1 WATER-IN-OIL EMULSIFIED COSMETIC PREPARATION Shiseido Co., Ltd. (JP) 2020-04-15 EP disclosed
US-20090136436-A1 FRAGRANCING COMPOSITION COMPRISING THE COMBINATION OF A HYDROXYAMINOBENZOPHENONE SCREEN A, A CINNAMATE SCREEN B AND A PIPERIDINOL, BENZOTRIAZOLE OR DIBENZOYLMETHANE COMPOUND C L'OREAL (FR) 2009-05-28 US disclosed
EP-1994921-A1 Fragrance composition comprising the combination of one filter A hydroxyaminobenzophenone, one filter B cinnamate and of one compound C piperidinole, benzotriazole or dibenzoylmethane L'Oreal (FR) 2008-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090136436-A1 FRAGRANCING COMPOSITION COMPRISING THE COMBINATION OF A HYDROXYAMINOBENZOPHENONE SCREEN A, A CINNAMATE SCREEN B AND A PIPERIDINOL, BENZOTRIAZOLE OR DIBENZOYLMETHANE COMPOUND C DDC, SUCLG1, TRPA1 BID 1623/4885MCL1 3786/4885BCL2L1 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.