SCHEMBL420045

SCHEMBL420045

C=C1C=CC=CC1Nc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CTSD P07339 1/20 0.31
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC6A2 P23975 1/20 0.30
MAPK1 P28482 1/20 0.30
PTGS2 P35354 1/20 0.30
HTR2B P41595 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28392491 0.90 NFKB1 (0.35) NFKB1NFKB2RELARECQLSMN1; SMN2
Glycidol SCHEMBL28089832 0.83 NFKB1 (0.31) NFKB1NFKB2RELAMAPK1
SCHEMBL29003530 0.79 CA1 (0.38) NFKB1NFKB2RELA
SCHEMBL28333387 0.77 NFKB1 (0.37) NFKB1NFKB2RELARECQLSMN1; SMN2
Formaldehyde SCHEMBL1304276 0.74 NFKB1 (0.36) NFKB1NFKB2RELARECQLSMN1; SMN2
SCHEMBL31514269 0.73 NFKB1 (0.38) NFKB1NFKB2RELARECQLSMN1; SMN2
SCHEMBL27405297 0.73 NFKB1 (0.38) NFKB1NFKB2RELARECQLSMN1; SMN2
SCHEMBL28833044 0.73 NFKB1 (0.34) NFKB1NFKB2RELARECQLSMN1; SMN2
SCHEMBL27633331 0.73 NFKB1 (0.38) NFKB1NFKB2RELARECQLSMN1; SMN2
SCHEMBL27405844 0.73 NFKB1 (0.34) NFKB1NFKB2RELARECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 779 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12256206-B2 Diaphragm for sound producing device, sound producing device, and method for assembling the same GOERTEK INC. (CN) 2025-03-18 US claimed
CN-119092717-A Composite current collector, preparation method and application thereof 江西沃格光电股份有限公司 2024-12-06 CN claimed
CN-118745668-A Method for preparing conductive sun-shading material based on graft polymerization 浙江德易遮阳科技股份有限公司 2024-10-08 CN claimed
WO-2024133871-A1 PIR CHEMICAL RECYCLING BY ALKALINE CLEAVAGE RECTICEL (BE) 2024-06-27 WO claimed
US-20240018366-A1 ZINC RICH EPOXY COATING PPG COATINGS (KUNSHAN) CO., LTD. (CN) 2024-01-18 US claimed
CN-115650861-B Application of lignin-based polyurethane chain extender in preparation of polyurethane material 南京工业大学 2023-11-24 CN claimed
EP-4251703-A1 ZINC RICH EPOXY COATING PPG Coatings (kunshan) Co., Ltd. (CN) 2023-10-04 EP claimed
CN-116802054-A High-thickness multilayer polyimide film and preparation method thereof 聚酰亚胺先端材料有限公司 2023-09-22 CN claimed
US-20230262394-A1 DIAPHRAGM FOR SOUND PRODUCING DEVICE, SOUND PRODUCING DEVICE, AND METHOD FOR ASSEMBLING THE SAME GOERTEK INC. (CN) 2023-08-17 US claimed
CN-115650861-A Application of lignin-based polyurethane chain extender in preparation of polyurethane material 南京工业大学 2023-01-31 CN claimed
EP-1435366-B1 Polyisocyanurate foam and process for its preparation DOW GLOBAL TECHNOLOGIES INC (US) 2008-08-13 EP claimed
WO-2007071717-A2 ACID FUNCTIONAL POLYAMIDEIMIDES ALTANA ELECTRICAL INSULATION GMBH (DE) 2007-06-28 WO claimed
US-20070142616-A1 Acid functional polyamideimides MURRAY THOMAS J 2007-06-21 US claimed
US-6673970-B1 A DIISOCYANATE PREPARED BY PHOSGENATING THE METHYLENE DIPHENYLAMINE REACTION PRODUCT OF ANILINE AND FORMALDEHYDE IN THE PRESENCE OF AN ACID CATALYST BAYER POLYMERS LLC 2004-01-06 US claimed
EP-1167343-B1 Process for the production of an aromatic polyamine mixture BASF AG (DE) 2003-05-21 EP claimed
EP-1167343-A1 Process for the production of an aromatic polyamine mixture BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP claimed
US-6031136-A REACTING ANILINE AND FORMALDEHYDE IN THE PRESENCE OF AN ACID CATALYST; REDUCING THE ACID LEVEL BY COMPLETELY NEUTRALIZING THE REACTION PRODUCT AFTER DIGESTION; FOAMLESS BAYER CORPORATION (US) 2000-02-29 US claimed
US-5274004-A Thermally treating scrap with a liquid mixture of alkanolamine and metal hydroxide followed by reaction with an alkylene oxide THE DOW CHEMICAL COMPANY (US) 1993-12-28 US claimed
US-4994503-A Stable dispersion of polymer containing aminocarbonyl and aminothiocarbonyl groups in a continuous phase; reinforcement and fillers of polyurethane and/or-urea matrix THE DOW CHEMICAL COMPANY (US) 1991-02-19 US claimed
US-4081427-A POLYESTER-POLYIMIDE THE P. D. GEORGE COMPANY (US) 1978-03-28 US claimed