Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042573 | 0.75 | TAAR1 (0.52) | — | |
| SCHEMBL31702271 | 0.74 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL1499458 | 0.73 | CA1 (0.56) | ALDH1A1RAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL27507555 | 0.72 | CA12 (0.54) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL28917392 | 0.70 | CA1 (0.56) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL87450 | 0.70 | CA1 (0.83) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL25340952 | 0.70 | RAB9A (0.54) | ALDH1A1RAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL15231562 | 0.70 | ESR2 (0.51) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL4003420 | 0.70 | CA12 (0.59) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL31115506 | 0.69 | PDE4A (0.52) | ALDH1A1RAB9ASMN1; SMN2LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101875654-A | The preparation method of 3-acyl amino cumarone-2-carboxylic acid derivative | TANABE SEIYAKU CO | 2010-11-03 | — | — | CN | disclosed |
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | SEKI MASAHIKO | 2009-01-22 | — | — | US | disclosed |
| US-7439368-B2 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| CN-1842528-A | Process for preparing 3-acylaminobenzofuran-2-carboxylic acid derivatives | TANABE SEIYAKU CO (JP) | 2006-10-04 | — | — | CN | disclosed |
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-08-03 | — | — | US | disclosed |
| EP-1640373-A1 | PROCESS FOR PRODUCING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | F12, F3, F11 | ALDH1A1 661/4885RAB9A 2600/4885SMN1; SMN2 4062/4885 |
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | F12, F3, F11 | ALDH1A1 690/4885RAB9A 2586/4885SMN1; SMN2 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.