Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232801 | 0.79 | FFAR1 (0.44) | FFAR1ALDH1A1MTORTAAR1HDAC3 | |
| SCHEMBL1436108 | 0.76 | PTPN1 (0.54) | FFAR1ALDH1A1MTORTAAR1IDO1 | |
| SCHEMBL3310761 | 0.76 | ADH1B (0.55) | FFAR1ALDH1A1MTORTAAR1HDAC3 | |
| SCHEMBL7345712 | 0.75 | FFAR1 (0.68) | FFAR1ALDH1A1MTORPPARA | |
| SCHEMBL25588013 | 0.74 | ALDH1A1 (0.52) | FFAR1ALDH1A1MTORTAAR1HDAC3 | |
| SCHEMBL27982876 | 0.74 | ALDH1A1 (0.52) | FFAR1ALDH1A1MTORTAAR1HDAC3 | |
| Hydrochloric Acid SCHEMBL7347655 | 0.74 | IDO1 (0.52) | FFAR1ALDH1A1MTORTAAR1HDAC3 | |
| SCHEMBL29026424 | 0.73 | FFAR1 (0.49) | FFAR1MTORHDAC3HDAC1HDAC2 | |
| SCHEMBL296280 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TAAR1LSSIDO1KIF11 | |
| SCHEMBL20058285 | 0.72 | TAAR1 (0.48) | ALDH1A1TAAR1HDAC1HDAC8IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828223-A4 | NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | PANACOS PHARMACEUTICALS INC (US) | 2009-03-11 | — | — | EP | disclosed |
| EP-1828223-A2 | NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | Panacos Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006053255-A2 | NOVEL BETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | PANACOS PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | disclosed |