Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253414 | 0.91 | LPAR1 (0.52) | LPAR1LPAR5MAPK14KDM4ESRD5A2 | |
| SCHEMBL20510924 | 0.87 | POLB (0.51) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL14967208 | 0.86 | LPAR1 (0.72) | LPAR1LPAR5MAPK14POLBGAA | |
| SCHEMBL27860600 | 0.85 | POLB (0.49) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL9745478 | 0.83 | SMN1; SMN2 (0.58) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL9745662 | 0.83 | SMN1; SMN2 (0.58) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL669346 | 0.82 | SMN1; SMN2 (0.57) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL29024996 | 0.82 | MAPK14 (0.48) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL27657687 | 0.81 | SMN1; SMN2 (0.53) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 | |
| SCHEMBL14094394 | 0.81 | SMN1; SMN2 (0.44) | LPAR1LPAR5MAPK14KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659628-B | Phthalonitrile monomer containing aromatic polyamide, synthetizing method thereof and poly phthalonitrile resin produced through solidification of phthalonitrile monomer | UNIV SICHUAN | 2014-07-02 | — | — | CN | disclosed |
| US-8741264-B2 | Self-sterilizing products | MOLTENI THERAPEUTICS S.R.L. (IT) | 2014-06-03 | — | — | US | disclosed |
| EP-1904109-B1 | SELF-STERILIZING PRODUCTS | MOLTENI & C (IT) | 2013-04-03 | — | — | EP | disclosed |
| CN-102659628-A | Phthalonitrile monomer containing aromatic polyamide, synthetizing method thereof and poly phthalonitrile resin produced through solidification of phthalonitrile monomer | UNIV SICHUAN | 2012-09-12 | — | — | CN | disclosed |
| US-20090130049-A1 | Self-Sterilizing Products | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) | 2009-05-21 | — | — | US | disclosed |
| EP-1904109-A1 | SELF-STERILIZING PRODUCTS | L. Molteni&c. dei Fratelli Alitti Societa' di Eserss (IT) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007000472-A1 | SELF-STERILIZING PRODUCTS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130049-A1 | Self-Sterilizing Products | NASP, ZP1, SPAG5 | LPAR1 4793/4885LPAR5 4599/4885MAPK14 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.