Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678813 | 0.87 | MAP2K1 (0.54) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL4190015 | 0.85 | MAP2K1 (0.52) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL27563134 | 0.84 | MAP2K1 (0.56) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL30713630 | 0.84 | MAP2K1 (0.51) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL27750328 | 0.84 | MAP2K1 (0.51) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL12491066 | 0.79 | AXL (0.51) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL820352 | 0.78 | AXL (0.55) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL30068926 | 0.78 | AXL (0.55) | MAP2K1MTNR1AGRM8GRM4KMT2A | |
| SCHEMBL1327936 | 0.78 | GPR84 (0.54) | KMT2AGPR84 | |
| SCHEMBL29800817 | 0.78 | GPR84 (0.54) | KMT2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467612-B | Simple preparation method of prostaglandin D2 receptor inhibitor compound | 新发药业有限公司 | 2020-09-25 | — | — | CN | disclosed |
| EP-2032578-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | Pfizer Products Incorporated (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007138472-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138472-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-12-06 | — | — | WO | disclosed |