SCHEMBL4201862

SCHEMBL4201862

CC(C)NC(=O)Nc1cccc(S(=O)(=O)Nc2ccccc2CN[C@@H](C)CC2CCCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.50
MAPT P10636 5/20 0.50
MAPK1 P28482 3/20 0.50
TP53 P04637 1/20 0.50
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
ALDH1A1 P00352 5/20 0.43
HTT P42858 2/20 0.43
KDM4E B2RXH2 3/20 0.41
PKM P14618 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALOX12 P18054 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPY1R P25929 2/20 0.40
HPGD P15428 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4189913 0.87 KDM4E (0.45) LMNAMAPTMAPK1TP53MEN1
SCHEMBL4197659 0.84 KMT2A (0.47) LMNAMAPTMAPK1TP53MEN1
SCHEMBL12050344 0.83 KDM4E (0.55) LMNAMAPTMEN1KMT2AALDH1A1
SCHEMBL4194146 0.83 PKM (0.46) LMNAMAPTMAPK1TP53MEN1
SCHEMBL4196629 0.82 KMT2A (0.48) MEN1KMT2AALDH1A1HTTNPSR1
SCHEMBL4197445 0.82 KMT2A (0.48) MEN1KMT2AALDH1A1HTTNPSR1
SCHEMBL4195095 0.82 KMT2A (0.48) MEN1KMT2AALDH1A1HTTNPSR1
SCHEMBL4194882 0.82 KDM4E (0.41) LMNAMAPTMAPK1TP53MEN1
SCHEMBL4197992 0.81 MEN1 (0.42) LMNAMAPTMAPK1TP53MEN1
SCHEMBL14343791 0.81 PKM (0.52) LMNAMEN1KMT2AKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 LMNA 2332/4885MAPT 2269/4885MAPK1 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.