Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201901 | 1.00 | CTSK (0.59) | CTSKCTSSPIK3CDPOLBABCB1 | |
| SCHEMBL4207288 | 1.00 | CTSK (0.59) | CTSKCTSSPIK3CDPOLBABCB1 | |
| SCHEMBL4212871 | 0.83 | CTSK (0.55) | CTSKCTSSPIK3CDPOLBABCB1 | |
| SCHEMBL5941514 | 0.81 | CTSK (0.64) | CTSKCTSSPIK3CDABCB1ABCG2 | |
| SCHEMBL4048380 | 0.81 | CTSK (0.64) | CTSKCTSSPIK3CDABCB1ABCG2 | |
| SCHEMBL5942080 | 0.79 | CTSK (0.88) | CTSKCTSS | |
| SCHEMBL5942073 | 0.79 | CTSK (0.88) | CTSKCTSS | |
| SCHEMBL4207960 | 0.79 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4207958 | 0.79 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4218204 | 0.78 | CTSK (0.59) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| WO-2007023281-A2 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131502-A1 | Biologically active compounds | COLGALT1, SOST, COL1A1 | CTSK 116/4885CTSS 52/4885PIK3CD 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.