Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4193559 | 0.99 | CCR5 (0.65) | CCR5OPRM1KCNH2 | |
| SCHEMBL13853336 | 0.94 | CCR5 (0.58) | CCR5OPRM1KCNH2 | |
| SCHEMBL13853345 | 0.91 | CCR5 (0.68) | CCR5OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL4187701 | 0.91 | CCR5 (0.67) | CCR5OPRM1KCNH2 | |
| SCHEMBL4205859 | 0.89 | CCR5 (0.55) | CCR5KCNH2 | |
| SCHEMBL13853346 | 0.88 | CCR5 (0.64) | CCR5OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL4194618 | 0.88 | CCR5 (0.63) | CCR5OPRM1KCNH2 | |
| SCHEMBL4189872 | 0.87 | CCR5 (0.58) | CCR5KCNH2 | |
| SCHEMBL13853331 | 0.86 | CCR5 (0.61) | CCR5OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL4194670 | 0.86 | CCR5 (0.60) | CCR5OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CCR2 | CCR5 1/4885OPRM1 60/4885KCNH2 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.