SCHEMBL4202102

SCHEMBL4202102

CCO[Si](CC)(NC1CCCCC1C)OCC

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
ALDH1A1 P00352 1/20 0.32
EPHX1 P07099 1/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.30
TAS1R2 Q8TE23 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4217740 0.86 TAS1R3 (0.33) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4205640 0.86 POLB (0.33) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4204908 0.84 POLB (0.35) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4215271 0.83 POLB (0.34) TAS1R3TAS1R1POLB
SCHEMBL4210283 0.81 TAS1R3 (0.35) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL5148530 0.80 TAS1R3 (0.35) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4361773 0.77 TAS1R3 (0.33) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4215225 0.77 THRB (0.32) ALDH1A1
SCHEMBL4207831 0.76 TAS1R3 (0.33) TAS1R3TAS1R1ALDH1A1EPHX1POLB
SCHEMBL4205264 0.76 EPHX1 (0.33) TAS1R3TAS1R1ALDH1A1EPHX1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed