SCHEMBL420260

SCHEMBL420260

NC1CCCCC1(N)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
BLM P54132 1/20 0.41
CACNA2D1 P54289 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP2C19 P33261 2/20 0.39
POLB P06746 1/20 0.33
HSD11B1 P28845 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9537043 1.00 CYP1A2 (0.41) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL9537041 1.00 CYP1A2 (0.41) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL11143116 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL4043871 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL3775732 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL9301362 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1USP2LMNATSHR
Water SCHEMBL10639693 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1USP2LMNATSHR
Acetic Acid SCHEMBL9484548 0.93 CYP1A2 (0.37) CYP1A2ALDH1A1USP2LMNATSHR
Acetic Acid SCHEMBL10419545 0.93 CYP1A2 (0.37) CYP1A2ALDH1A1USP2LMNATSHR
SCHEMBL9320553 0.85 CYP2C19 (0.33) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7537857-B2 Reduced degradation of ion-exchange membranes in electrochemical fuel cells BDF IP HOLDINGS LTD. (CA) 2009-05-26 US claimed
US-6030840-A CONTACTING CHELATED LANTHANIDE METAL IONS BOUND TO MARKER WITH BUFFERED SOLUTION OF DETERGENT, ENHANCER REAGENT AND POLYANION; IONS DISSOCIATE FROM MARKER AND REASSOCIATE WITH ENHANCER; THEN DETERMINING AMOUNT OF IONS LIBERATED NEN LIFE SCIENCES, INC. (US) 2000-02-29 US claimed
WO-1999066333-A1 NEUTRAL ENHANCEMENT OF LANTHANIDES FOR TIME RESOLVED FLUORESCENCE NEN LIFE SCIENCE PRODUCTS, INC. (US) 1999-12-23 WO claimed
EP-0150844-B1 METHOD OF RADIOACTIVELY LABELING DIAGNOSTIC AND THERAPEUTIC AGENTS CONTAINING A CHELATING GROUP ENZO BIOCHEM, INC. (US) 1993-07-28 EP claimed
US-4772548-A Radioisotopicassay using isotope transfer to chelator-target recognition molecule conjugate ENZO BIOCHEM, INC. (US) 1988-09-20 US claimed
US-4767609-A Therapeutic and diagnostic processes using isotope transfer to chelator-target recognition molecule conjugate ENZO BIOCHEM, INC. (US) 1988-08-30 US claimed
US-4707352-A Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group ENZO BIOCHEM, INC. (US) 1987-11-17 US claimed
EP-0150844-A2 Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group ENZO BIOCHEM, INC. (US) 1985-08-07 EP claimed
US-11613551-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders ELOXX PHARMACEUTICALS LTD. (IL) 2023-03-28 US disclosed
CN-107922454-B Dual quencher probes 生物检索技术股份有限公司 2021-10-22 CN disclosed
US-20210300958-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2021-09-30 US disclosed
EP-3883943-A1 MODIFIED AMINOGLYCOSIDE COMPOUNDS AND USES THEREOF IN DISABLING BACTERIAL RIBOSOME Technion Research & Development Foundation Limited (IL) 2021-09-29 EP disclosed
US-20210275557-A1 MODIFIED AMINOGLYCOSIDE COMPOUNDS AND USES THEREOF IN DISABLING BACTERIAL RIBOSOME TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2021-09-09 US disclosed
US-10899785-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders ELOXX PHARMACEUTICALS LTD. (IL) 2021-01-26 US disclosed
US-4772548-A Radioisotopicassay using isotope transfer to chelator-target recognition molecule conjugate ENZO BIOCHEM, INC. (US) 1988-09-20 US disclosed
US-4767609-A Therapeutic and diagnostic processes using isotope transfer to chelator-target recognition molecule conjugate ENZO BIOCHEM, INC. (US) 1988-08-30 US disclosed
EP-0258616-A1 NMR Imaging with paramagnetic polyvalent metal salts of poly-(acid-alkylene-amino)-alkanes SALUTAR, INC. (US) 1988-03-09 EP disclosed
US-4707352-A Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group ENZO BIOCHEM, INC. (US) 1987-11-17 US disclosed
EP-0150844-A2 Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group ENZO BIOCHEM, INC. (US) 1985-08-07 EP disclosed
US-4049585-A BUILDERS, LOW SUDSING THE PROCTER & GAMBLE COMPANY (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210275557-A1 MODIFIED AMINOGLYCOSIDE COMPOUNDS AND USES THEREOF IN DISABLING BACTERIAL RIBOSOME FBL, MRPL21, NOP2 CYP1A2 4233/4885ALDH1A1 1534/4885USP2 4503/4885
US-20210300958-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS UPF1, AARS1, NUDT21 CYP1A2 2733/4885ALDH1A1 1473/4885USP2 4425/4885
US-11613551-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders UPF1, AARS1, NUDT21 CYP1A2 2733/4885ALDH1A1 1473/4885USP2 4425/4885
US-10899785-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders UPF1, AARS1, NUDT21 CYP1A2 2733/4885ALDH1A1 1473/4885USP2 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.