Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20427919 | 0.78 | PDE4D (0.43) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL2087514 | 0.77 | PKM (0.34) | KDM4EMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL15158194 | 0.77 | PTGER4 (0.37) | KDM4EMAPTMEN1KMT2APTGER4 | |
| SCHEMBL2721935 | 0.75 | KDM4E (0.44) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL1335845 | 0.74 | KDM4E (0.60) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL20427928 | 0.74 | CYP1A2 (0.60) | KDM4EMAPTL3MBTL1ALDH1A1POLB | |
| Fluoride SCHEMBL8759650 | 0.73 | KDM4E (0.43) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27700440 | 0.73 | KDM4E (0.43) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10341079 | 0.72 | KDM4E (0.58) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL4350886 | 0.72 | KDM4E (0.45) | KDM4EMAPTL3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105325-A1 | Substituted Pyrazolecarboxylic Acid Anilide Derivative or Salt Thereof, Intermediate Thereof, Agent for Agricultural and Horticultural Use, and Use Thereof | NIHON NOHYAKU CO., LTD. (JP) | 2009-04-23 | — | — | US | claimed |
| EP-1925613-A1 | SUBSTITUTED PYRAZOLECARBOXYLIC ACID ANILIDE DERIVATIVE OR SALT THEREOF, INTERMEDIATE THEREOF, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2008-05-28 | — | — | EP | claimed |
| US-10035773-B2 | Method for producing 3,5-bis(fluoroalkyl)-pyrazol-4-carboxylic acid derivatives and 3,5-bis(fluoroalkyl)-pyrazoles | BAYER CROPSCIENCE AG (DE) | 2018-07-31 | — | — | US | disclosed |
| EP-1925613-B1 | SUBSTITUTED PYRAZOLECARBOXYLIC ACID ANILIDE DERIVATIVE OR SALT THEREOF, INTERMEDIATE THEREOF, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND USE THEREOF | NIHON NOHYAKU CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-8404861-B2 | Substituted pyrazolecarboxylic acid anilide derivative or salt thereof, intermediate thereof, agent for agricultural and horticultural use, and use thereof | NIHON NOHYAKU CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| CN-101243049-B | Substituted pyrazolecarboxylic acid anilide derivative or salt thereof, intermediate thereof, agent for agricultural and horticultural use, and use thereof | NIHON NOHYAKU CO LTD | 2011-11-16 | — | — | CN | disclosed |
| US-20090105325-A1 | Substituted Pyrazolecarboxylic Acid Anilide Derivative or Salt Thereof, Intermediate Thereof, Agent for Agricultural and Horticultural Use, and Use Thereof | NIHON NOHYAKU CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| CN-101243049-A | Substituted pyrazolecarboxylic acid anilide derivative or salt thereof, intermediate thereof, agent for agricultural and horticultural use, and use thereof | NIHON NOHYAKU CO LTD (JP) | 2008-08-13 | — | — | CN | disclosed |
| EP-1925613-A1 | SUBSTITUTED PYRAZOLECARBOXYLIC ACID ANILIDE DERIVATIVE OR SALT THEREOF, INTERMEDIATE THEREOF, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035773-B2 | Method for producing 3,5-bis(fluoroalkyl)-pyrazol-4-carboxylic acid derivatives and 3,5-bis(fluoroalkyl)-pyrazoles | KYAT3, AADAC, CYP3A5 | KDM4E 3193/4885MAPT 2762/4885L3MBTL1 4801/4885 |
| US-20090105325-A1 | Substituted Pyrazolecarboxylic Acid Anilide Derivative or Salt Thereof, Intermediate Thereof, Agent for Agricultural and Horticultural Use, and Use Thereof | AS3MT, SETD7, CBR3 | KDM4E 1412/4885MAPT 4038/4885L3MBTL1 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.