Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203158 | 0.77 | KDM4E (0.41) | PKMMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL12499736 | 0.77 | SRD5A2 (0.46) | — | |
| SCHEMBL12499378 | 0.76 | MAPT (0.40) | MAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9199894 | 0.75 | GAA (0.36) | GAAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8304267 | 0.74 | L3MBTL1 (0.44) | MAPTGAAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1496038 | 0.74 | GAA (0.52) | PKMGAAGABRPGABRDGABRA1 | |
| SCHEMBL15158194 | 0.73 | PTGER4 (0.37) | PKMMAPTKDM4EGRNSORT1 | |
| SCHEMBL12499826 | 0.73 | CCR2 (0.39) | — | |
| SCHEMBL12498747 | 0.73 | AADAT (0.43) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12499705 | 0.72 | HCAR2 (0.42) | PKMMAPTCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854788-B1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEM RES (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-7863460-B2 | Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1854788-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | CYP4Z1, CYP3A4, HACL2 | PKM 423/4885MAPT 2978/4885GAA 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.