SCHEMBL4203207

SCHEMBL4203207

CCCOC(=O)c1cccc2nnsc12

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
MAPK1 P28482 3/20 0.47
TSHR P16473 7/20 0.45
TDP1 Q9NUW8 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP3A4 P08684 2/20 0.44
TP53 P04637 1/20 0.44
LMNA P02545 2/20 0.43
HSD17B10 Q99714 3/20 0.40
PDK2 Q15119 1/20 0.40
KDM4E B2RXH2 4/20 0.39
POLB P06746 2/20 0.39
ESR1 P03372 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
KDR P35968 1/20 0.39
MAOB P27338 1/20 0.39
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530686 0.95 ALDH1A1 (0.50) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9084604 0.92 TSHR (0.57) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9087303 0.91 MAPK1 (0.59) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9087862 0.89 TSHR (0.53) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9086816 0.86 MAPK1 (0.40) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL30996828 0.85 ACHE (0.40) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL30996829 0.85 ACHE (0.40) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9086720 0.85 MAPK1 (0.43) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL9088671 0.83 MAPK1 (0.36) ALDH1A1MAPK1TSHRTDP1L3MBTL1
SCHEMBL7243970 0.83 PKM (0.37) ALDH1A1MAPK1TSHRL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003033712-A1 CHEMICALLY INDUCIBLE PROMOTERS FROM BARLEY AND USE THEREOF BASF PLANT SCIENCE GMBH (DE) 2003-04-24 WO claimed
US-5851766-A Process for isolating chemically regulatable DNA sequences NOVARTIS FINANCE CORPORATION (US) 1998-12-22 US claimed
US-5804693-A TRANSGENIC PLANT, PLANT CELL OR PLANT TISSUE COMPRISING AN ENCODED ENZYME CAPABLE METABOLIZING SALICYLIC ACID NOVARTIS FINANCE CORPORATION (US) 1998-09-08 US claimed
US-5789214-A TRANSPORTATION OF PLANT TISSUES, NUCLEIC ACID PROMOTER FRAGMENTS, CODES AND EXPOSING TISSUES NOVARTIS FINANCE CORPORATION (US) 1998-08-04 US claimed
US-5777200-A Chemically regulatable and anti-pathogenic DNA sequences and uses thereof NOVARTIS FINANCE CORPORATION (US) 1998-07-07 US claimed
US-5614395-A SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS CIBA-GEIGY CORPORATION (US) 1997-03-25 US claimed
US-5190928-A Benzo-1,2,3-thiadiazoles CIBA-GEIGY CORPORATION (US) 1993-03-02 US claimed
EP-0313512-B1 BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES CIBA-GEIGY AG (CH) 1992-11-25 EP claimed
EP-0332104-A2 Chemically regulatable DNA sequences and genes and uses thereof CIBA-GEIGY AG (CH) 1989-09-13 EP claimed
EP-0313512-A2 Benzothiadiazoles and their use in processes and compositions against plant diseases CIBA-GEIGY AG (CH) 1989-04-26 EP claimed
WO-2009095098-A2 USE OF BENZOTHIADIAZOLES RWTH AACHEN (DE) 2009-08-06 WO disclosed
US-7361806-B2 Transgenic plants expressing a cellulase SYNGENTA PARTICIPATIONS AG (CH) 2008-04-22 US disclosed
US-7030294-B2 Heterologous expression cassette of a nucleotide sequence under control of an inducible promoter SYNGENTA PARTICIPATIONS AG (CH) 2006-04-18 US disclosed
EP-1574580-A2 Transgenic plants expressing cellulolytic enzymes Syngenta Participations AG (CH) 2005-09-14 EP disclosed
EP-0925362-B1 TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES SYNGENTA PARTICIPATIONS AG (CH) 2005-07-20 EP disclosed
US-5190928-A Benzo-1,2,3-thiadiazoles CIBA-GEIGY CORPORATION (US) 1993-03-02 US disclosed
EP-0313512-B1 BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES CIBA-GEIGY AG (CH) 1992-11-25 EP disclosed
US-4931581-A CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES CIBA-GEIGY CORPORATION (US) 1990-06-05 US disclosed
EP-0332104-A2 Chemically regulatable DNA sequences and genes and uses thereof CIBA-GEIGY AG (CH) 1989-09-13 EP disclosed
EP-0313512-A2 Benzothiadiazoles and their use in processes and compositions against plant diseases CIBA-GEIGY AG (CH) 1989-04-26 EP disclosed