Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204182 | 1.00 | TSHR (0.38) | TSHRMEN1KMT2ATRPM8GAA | |
| SCHEMBL11653156 | 0.70 | TSHR (0.37) | TSHRTRPM8PHGDH | |
| SCHEMBL4209002 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL4209001 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL1717476 | 0.62 | TSHR (0.42) | TSHRMEN1KMT2ATRPM8GAA | |
| SCHEMBL4209061 | 0.61 | CA12 (0.36) | — | |
| SCHEMBL4209058 | 0.61 | CA12 (0.36) | — | |
| SCHEMBL6063380 | 0.60 | GSR (0.36) | MEN1KMT2AGSRPHGDHMGLL | |
| SCHEMBL28807494 | 0.59 | KMT2A (0.36) | TSHRMEN1KMT2AGSRADH1C | |
| SCHEMBL1712105 | 0.59 | SPHK1 (0.47) | TSHRMEN1KMT2ATRPM8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018364-A1 | METHOD FOR NITRATING ISOUREA | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1997802-A1 | METHOD FOR NITRATING ISOUREA | Sumitomo Chemical Company, Limited (JP) | 2008-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018364-A1 | METHOD FOR NITRATING ISOUREA | NIT2, NOS3, NOS2 | TSHR 106/4885MEN1 1598/4885KMT2A 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.