Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22532336 | 0.90 | TSHR (0.41) | ALDH1A1HPGDPI4KBRXFP1NPC1 | |
| SCHEMBL25389524 | 0.82 | LCK (0.46) | ALDH1A1PI4KBTSHRLCK | |
| SCHEMBL4301296 | 0.71 | CDK2 (0.46) | SMN1; SMN2LMNA | |
| SCHEMBL24599388 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDPI4KBRXFP1PIK3CG | |
| SCHEMBL12620553 | 0.70 | ALDH1A1 (0.58) | ALDH1A1HPGDPI4KBRXFP1PIK3CG | |
| SCHEMBL924824 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HPGDRXFP1PIK3CGPIK3CD | |
| SCHEMBL155142 | 0.69 | RAB9A (0.57) | ALDH1A1HPGDRXFP1PIK3CGPIK3CD | |
| SCHEMBL24599484 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HPGDPI4KBRXFP1PIK3CG | |
| SCHEMBL15939461 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HPGDPI4KBRXFP1PIK3CG | |
| SCHEMBL21552109 | 0.68 | PDE2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029997-A1 | Thiazole Derivatives and Use Thereof | LABORATOIRES SERONO SA (CH) | 2009-01-29 | — | — | US | disclosed |
| EP-1979346-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007082956-A1 | THIAZOLE DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029997-A1 | Thiazole Derivatives and Use Thereof | PDGFRB, PDGFRA, TEC | ALDH1A1 174/4885HPGD 2130/4885PI4KB 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.