SCHEMBL4206573

SCHEMBL4206573

CC(C)(C)c1cc(Br)c2c(c1)C(C)(C)c1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.42
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRB1 P08588 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL807031 0.85 ALDH1A1 (0.35) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL27290040 0.80 PDK2 (0.59) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL16544760 0.79 NPC1 (0.41) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL29556912 0.79 NPC1 (0.41) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL17816859 0.78 NPC1 (0.40) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL4196568 0.77 ALDH1A1 (0.35) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL13278527 0.76 ALDH1A1 (0.50) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL15213960 0.76 PDK2 (0.43) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL808128 0.75 PDK2 (0.54) PDK2ALDH1A1L3MBTL1MLNRNR1I2
SCHEMBL29364892 0.75 PDK2 (0.54) PDK2ALDH1A1L3MBTL1MLNRNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096210-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2023-06-01 WO disclosed
EP-3904361-A2 BORON CONTAINING COMPOUNDS Merck Patent GmbH (DE) 2021-11-03 EP disclosed
EP-3052505-B1 BORON-CONTAINING COMPOUNDS MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20160248015-A1 BORON-CONTAINING COMPOUNDS MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
US-20160248015-A1 BORON-CONTAINING COMPOUNDS MERCK PATENT GMBH (DE) 2016-08-25 US disclosed
WO-2015049030-A2 BORON-CONTAINING COMPOUNDS MERCK PATENT GMBH (DE) 2015-04-09 WO disclosed
US-8072137-B2 Fused heterocyclic compound and organic light emitting device CANON KABUSHIKI KAISHA (JP) 2011-12-06 US disclosed
US-20090121625-A1 FUSED HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160248015-A1 BORON-CONTAINING COMPOUNDS BIRC2, BRSK1, CTCF PDK2 2955/4885NPC1 1106/4885ALDH1A1 3791/4885
US-20090121625-A1 FUSED HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE TYR, CRY1, LAGE3 PDK2 2469/4885NPC1 2223/4885ALDH1A1 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.