Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157692 | 0.88 | CYP2C19 (0.33) | TP53CYP3A4CYP2C19 | |
| SCHEMBL19971067 | 0.78 | MAPK1 (0.31) | TP53MAPK1NFKB1CYP2C19THPO | |
| SCHEMBL29424679 | 0.77 | TP53 (0.68) | TP53CYP3A4LMNA | |
| SCHEMBL27383022 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL20913174 | 0.71 | MAPK1 (0.31) | TP53MAPK1NFKB1CYP2C19THPO | |
| SCHEMBL4879516 | 0.68 | — | — | |
| SCHEMBL1537799 | 0.68 | CYP2C19 (0.50) | TP53CYP3A4CYP2C19LMNABLM | |
| SCHEMBL6429008 | 0.68 | TP53 (0.33) | TP53CYP3A4 | |
| Bicarbonate SCHEMBL10352400 | 0.67 | TFPI2 (0.50) | TP53MAPK1NFKB1CYP2C19THPO | |
| Bicarbonate SCHEMBL2914629 | 0.67 | TFPI2 (0.50) | TP53MAPK1NFKB1CYP2C19THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571561-B1 | INFLATION MEDIA FOR IMPLANTS | DFM LLC (US) | 2018-10-17 | — | — | EP | disclosed |
| US-20170172735-A1 | INFLATION MEDIA FOR IMPLANTS | DIRECT FLOW (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC | 2017-06-22 | — | — | US | disclosed |
| US-9433501-B2 | Inflation media for implants | DIRECT FLOW MEDICAL, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| EP-2571561-A2 | INFLATION MEDIA FOR IMPLANTS | Direct Flow Medical, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20120022629-A1 | INFLATION MEDIA FOR IMPLANTS | DIRECT FLOW MEDICAL, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2011146759-A2 | INFLATION MEDIA FOR IMPLANTS | DIRECT FLOW MEDICAL, INC. (US) | 2011-11-24 | — | — | WO | disclosed |