Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10352400 | 1.00 | TFPI2 (0.50) | TFPI2LMNAGMNNPMP22TP53 | |
| Malonic Acid SCHEMBL28486862 | 0.84 | LDHA (0.45) | TFPI2LMNAGMNNPMP22TP53 | |
| SCHEMBL12203926 | 0.83 | — | — | |
| SCHEMBL7933931 | 0.83 | — | — | |
| SCHEMBL3219 | 0.83 | — | — | |
| SCHEMBL12334971 | 0.83 | ALDH1A1 (0.36) | TFPI2LMNAGMNNPMP22TP53 | |
| SCHEMBL14844281 | 0.83 | — | — | |
| SCHEMBL2183062 | 0.83 | — | — | |
| SCHEMBL272959 | 0.83 | — | — | |
| Acrylic Acid SCHEMBL7698444 | 0.82 | LMNA (0.48) | TFPI2LMNAGMNNPMP22TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112421185-A | Electrolyte of non-negative secondary lithium battery, non-negative secondary lithium battery and formation process | 中国科学院青岛生物能源与过程研究所 | 2021-02-26 | — | — | CN | claimed |
| EP-3312214-B1 | METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT | IMPERIAL INNOVATIONS LTD (GB) | 2023-08-16 | — | — | EP | disclosed |
| CN-112421185-A | Electrolyte of non-negative secondary lithium battery, non-negative secondary lithium battery and formation process | 中国科学院青岛生物能源与过程研究所 | 2021-02-26 | — | — | CN | disclosed |
| WO-2021029341-A1 | FIRING PASTE RESIN COMPOSITION AND PASTE COMPOSITION | 住友精化株式会社 | 2021-02-18 | — | — | WO | disclosed |
| CN-106939078-B | Polymer compositions and methods | 沙特阿美技术公司 | 2020-12-11 | — | — | CN | disclosed |
| EP-3312214-A1 | METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT | Imperial Innovations Limited (GB) | 2018-04-25 | — | — | EP | disclosed |
| EP-2753651-B1 | METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT | IMP INNOVATIONS LTD (GB) | 2017-07-12 | — | — | EP | disclosed |
| US-9006347-B2 | Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent | IMPERIAL INNOVATIONS LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-20140249279-A1 | METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT | IMPERIAL INNOVATIONS LIMITED (GB) | 2014-09-04 | — | — | US | disclosed |
| CN-103058981-B | Cyclohexene carbonate high-efficiency catalytic synthesis method employing load-type catalyst | UNIV ZHENGZHOU | 2014-08-06 | — | — | CN | disclosed |
| EP-0057162-A1 | Process for the production of images | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | disclosed |
| EP-0054509-A2 | Salt of sulfoxonium as a polymerisation catalyst | CIBA-GEIGY AG (CH) | 1982-06-23 | — | — | EP | disclosed |
| EP-0051561-A1 | Resinlike salts, their preparation and their use in coatings | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |
| EP-0000971-B1 | POUDERY COATING COMPOSITION | CHEMISCHE WERKE HÜLS AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| EP-0044274-A2 | Photopolymerisation by means of carbamoylsulfoxonium salts | CIBA-GEIGY AG (CH) | 1982-01-20 | — | — | EP | disclosed |
| EP-0001148-B1 | METHOD OF COATING GLASS SURFACES | CHEMISCHE WERKE HÜLS AG (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0035969-A1 | Composition of cationically polymerisable material and a catalyst | CIBA-GEIGY AG (CH) | 1981-09-16 | — | — | EP | disclosed |
| EP-0024254-A1 | Aminotriazine polycarboxylic acids and their partial esters, their preparation and their use as hardening agents for epoxy resins | CIBA-GEIGY AG (CH) | 1981-02-25 | — | — | EP | disclosed |
| EP-0000971-A1 | Poudery coating composition | CHEMISCHE WERKE HÜLS AG (DE) | 1979-03-07 | — | — | EP | disclosed |
| US-4080476-A | ACRYLIC POLYMERS | DATASCOPE CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249279-A1 | METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT | TECR, MCM4, PCCA | TFPI2 1151/4885LMNA 3234/4885GMNN 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.