SCHEMBL4206972

SCHEMBL4206972

CC(C)n1ccc2cc(N3CC(CO)OC3=O)ccc21

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.55
MAOB P27338 2/20 0.55
CALML3 P27482 6/20 0.48
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
GRM2 Q14416 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4206970 1.00 MAOA (0.55) MAOAMAOBCALML3CYP3A4CYP2C19
SCHEMBL4210796 0.83 GRM2 (0.40) MAOAMAOBGRM2
SCHEMBL4210800 0.83 GRM2 (0.40) MAOAMAOBGRM2
SCHEMBL5337945 0.82 MAOA (0.56) MAOAMAOBCALML3CYP3A4CYP2C19
SCHEMBL5337955 0.82 MAOA (0.56) MAOAMAOBCALML3CYP3A4CYP2C19
SCHEMBL4201973 0.81 MAOA (0.56) MAOAMAOBCYP3A4
SCHEMBL4201967 0.81 MAOA (0.56) MAOAMAOBCYP3A4
SCHEMBL16686214 0.78 MAOA (0.56) MAOAMAOBCALML3CYP3A4CYP2C19
Lithium Ion SCHEMBL5337918 0.77 MAOA (0.50) MAOAMAOBCALML3CYP3A4CYP2C19
SCHEMBL9205426 0.76 MAOA (0.64) MAOAMAOBCALML3GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090149520-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS PFIZER INC 2009-06-11 US disclosed
EP-2004640-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS Pfizer Products Inc. (US) 2008-12-24 EP disclosed
WO-2007091147-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS PFIZER PRODUCTS INC. (US) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149520-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS OXA1L, MT-ND4L, IL4I1 MAOA 534/4885MAOB 709/4885CALML3 1933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.