Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | BCHE | P06276 | 11/20 | 0.60 |
| ▸ | ACHE | P22303 | 11/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4208306 | 1.00 | APP (0.64) | APPBCHEACHE | |
| SCHEMBL4365126 | 1.00 | APP (0.64) | APPBCHEACHE | |
| SCHEMBL4204714 | 0.99 | APP (0.64) | APPBCHEACHE | |
| SCHEMBL4371553 | 0.96 | APP (0.63) | APPBCHEACHE | |
| SCHEMBL4375004 | 0.92 | APP (0.54) | APPBCHEACHE | |
| SCHEMBL4364532 | 0.88 | APP (0.63) | APPBCHEACHE | |
| SCHEMBL4203085 | 0.88 | TGM2 (0.54) | APPBCHEACHE | |
| SCHEMBL4365817 | 0.87 | APP (0.63) | APPBCHEACHE | |
| SCHEMBL4376555 | 0.87 | BCHE (0.54) | APPBCHEACHE | |
| SCHEMBL4367367 | 0.86 | APP (0.73) | APPBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093521-A1 | 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives | ALMA MATER STUDIORUM - UNIVERISTA'DI BOLOGNA (IL) | 2009-04-09 | — | — | US | disclosed |
| EP-1890995-A2 | SYNTHESIS OF ORGANIC COMPOUNDS | Alma Mater Studiorum -Universita' di Bologna (IT) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006134457-A2 | 2,5-BIS-DIAMIMNE [1 , 4] BENZOQUINONE-DERIVATIVES | ALMA MATER STUDIORUM-UNIVERSITA' DI BOLOGNA (IT) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093521-A1 | 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives | POLQ, DDX5, SDHA | APP 3616/4885BCHE 2356/4885ACHE 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.