Sugi Predict

Sugi Predict / Compounds / Benzoquinone

Benzoquinone

Benzoquinone

SCHEMBL4207161

F.F.F.F.O=C1C=CC(=O)C=C1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.89
▸ TDP1 Q9NUW8 3/20 0.89
▸ RECQL P46063 2/20 0.89
▸ MAOA P21397 2/20 0.89
▸ MAOB P27338 2/20 0.89
▸ BCHE P06276 1/20 0.89
▸ POLB P06746 1/20 0.89
▸ ACHE P22303 1/20 0.89
▸ APEX1 P27695 1/20 0.89
▸ MAPK1 P28482 1/20 0.89
▸ CASP1 P29466 1/20 0.89
▸ BLM P54132 1/20 0.89
▸ MDM2 Q00987 1/20 0.89
▸ DHODH Q02127 1/20 0.89
▸ HSD17B10 Q99714 1/20 0.89
▸ APOBEC3G Q9HC16 1/20 0.89
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL18103 0.94 — —
Benzoquinone SCHEMBL3208089 0.94 — —
Benzoquinone SCHEMBL30679171 0.94 — —
Benzoquinone SCHEMBL31213285 0.89 — —
Benzoquinone SCHEMBL31324224 0.89 ALDH1A1 (0.89) ALDH1A1TDP1RECQLMAOAMAOB
Benzoquinone SCHEMBL31324208 0.89 ALDH1A1 (0.89) ALDH1A1TDP1RECQLMAOAMAOB
Benzoquinone SCHEMBL31324203 0.89 ALDH1A1 (0.89) ALDH1A1TDP1RECQLMAOAMAOB
Benzoquinone SCHEMBL31499513 0.89 — —
Benzoquinone SCHEMBL31324200 0.89 ALDH1A1 (0.89) ALDH1A1TDP1RECQLMAOAMAOB
Benzoquinone SCHEMBL7112416 0.89 ALDH1A1 (0.89) ALDH1A1TDP1RECQLMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090093521-A1 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives ALMA MATER STUDIORUM - UNIVERISTA'DI BOLOGNA (IL) 2009-04-09 — — US disclosed
EP-1890995-A2 SYNTHESIS OF ORGANIC COMPOUNDS Alma Mater Studiorum -Universita' di Bologna (IT) 2008-02-27 — — EP disclosed
WO-2006134457-A2 2,5-BIS-DIAMIMNE [1 , 4] BENZOQUINONE-DERIVATIVES ALMA MATER STUDIORUM-UNIVERSITA' DI BOLOGNA (IT) 2006-12-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093521-A1 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives POLQ, DDX5, SDHA ALDH1A1 151/4885TDP1 704/4885RECQL 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.