Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649212 | 0.87 | FAAH (0.40) | — | |
| Hydrochloric Acid SCHEMBL1768796 | 0.85 | FAAH (0.39) | — | |
| SCHEMBL28338925 | 0.84 | — | — | |
| SCHEMBL4195848 | 0.82 | CYP3A4 (0.40) | MEN1TSHRKMT2AAPLNR | |
| Hydrochloric Acid SCHEMBL21640729 | 0.82 | APLNR (0.32) | APLNR | |
| SCHEMBL408176 | 0.79 | TSHR (0.46) | MEN1TSHRKMT2AAPLNR | |
| SCHEMBL6893525 | 0.79 | — | — | |
| SCHEMBL16416154 | 0.78 | GBA1 (0.32) | TSHRAPLNR | |
| Hydrochloric Acid SCHEMBL440466 | 0.78 | TSHR (0.45) | MEN1TSHRKMT2AAPLNR | |
| SCHEMBL8134289 | 0.75 | MMP1 (0.33) | KMT2AAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032559-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007138268-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2007-12-06 | — | — | WO | disclosed |