Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894825 | 0.89 | — | — | |
| SCHEMBL4209196 | 0.88 | LMNA (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL133775 | 0.88 | — | — | |
| SCHEMBL5790232 | 0.88 | ALDH1A1 (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL133787 | 0.85 | — | — | |
| SCHEMBL25800877 | 0.85 | — | — | |
| SCHEMBL4205138 | 0.85 | ALDH1A1 (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL4201284 | 0.85 | ALDH1A1 (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL337639 | 0.85 | — | — | |
| SCHEMBL5531400 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828354-B1 | HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS | BASF SE (DE) | 2017-09-06 | — | — | EP | disclosed |
| US-8119840-B2 | Ethambutol based nitric oxide donors | THE UNIVERSITY OF AKRON (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119840-B2 | Ethambutol based nitric oxide donors | THE UNIVERSITY OF AKRON (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090235576-A1 | HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090069449-A1 | ETHAMBUTOL BASED NITRIC OXIDE DONORS | THE UNIVERSITY OF AKRON (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069449-A1 | ETHAMBUTOL BASED NITRIC OXIDE DONORS | THE UNIVERSITY OF AKRON (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1828354-A1 | HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063770-A1 | HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-22 | — | — | WO | disclosed |
| EP-1669433-A1 | Hydrocarbyl succinic acid and hydrocarbylsuccinic acid derivatives as friction modifiers | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-14 | — | — | EP | disclosed |
| EP-0726919-B1 | AQUEOUS PAINTS AND THEIR USE TO PRODUCE FILLER LAYERS IN AUTOMOBILE PAINTING | BASF COATINGS AG (DE) | 2001-06-06 | — | — | EP | disclosed |
| EP-0802244-A1 | Method for improving the brightness and levelling of lacquers | BASF Lacke + Farben AG (DE) | 1997-10-22 | — | — | EP | disclosed |
| EP-0726919-A1 | AQUEOUS PAINTS AND THEIR USE TO PRODUCE FILLER LAYERS IN AUTOMOBILE PAINTING | BASF Lacke + Farben AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0459125-B1 | Process for the preparation of diols containing perfluoroalkylrests and polyurethanes. | PFERSEE CHEM FAB (DE) | 1995-07-12 | — | — | EP | disclosed |
| WO-1995012626-A1 | AQUEOUS PAINTS AND THEIR USE TO PRODUCE FILLER LAYERS IN AUTOMOBILE PAINTING | BASF LACKE + FARBEN AG (DE) | 1995-05-11 | — | — | WO | disclosed |
| EP-0621881-A1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES). | MINNESOTA MINING & MFG (US) | 1994-11-02 | — | — | EP | disclosed |
| WO-1993015130-A2 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |
| EP-0467083-A2 | Perfluoroaliphatic group-containing copolymers with urethane and siloxane units | Pfersee Chemie GmbH (DE) | 1992-01-22 | — | — | EP | disclosed |
| EP-0459125-A1 | Process for the preparation of diols containing perfluoroalkylrests and polyurethanes. | Pfersee Chemie GmbH (DE) | 1991-12-04 | — | — | EP | disclosed |
| US-3970601-A | COATINGS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069449-A1 | ETHAMBUTOL BASED NITRIC OXIDE DONORS | NOS2, NOS1, NOS3 | LMNA 4788/4885CNR1 1050/4885ADRA1A 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.