Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273051 | 0.93 | PRKCA (0.48) | PRKCAMMP12GPR84PARP10CYP3A4 | |
| SCHEMBL4221778 | 0.92 | PRKCA (0.54) | PRKCAMMP12GPR84ALOX5PARP10 | |
| SCHEMBL2273056 | 0.89 | PRKCA (0.49) | PRKCAMMP12ALOX5PARP10CYP3A4 | |
| SCHEMBL2272974 | 0.85 | PRKCA (0.48) | PRKCAMMP12GPR84PARP10CYP3A4 | |
| SCHEMBL2278327 | 0.83 | PRKCA (0.62) | PRKCAMMP12GPR84CYP3A4CYP2C19 | |
| SCHEMBL3079634 | 0.83 | PRKCA (0.71) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL3080762 | 0.83 | PRKCA (0.71) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL4215913 | 0.82 | PRKCA (0.51) | PRKCAMMP12ALOX5CYP3A4CYP2C19 | |
| SCHEMBL3086850 | 0.80 | PRKCA (0.57) | PRKCAMMP12CYP3A4CYP2C19NR1I2 | |
| SCHEMBL772182 | 0.79 | PRKCA (0.51) | PRKCAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048239-A1 | Therapeutic compounds | MSD ITALIA S.R.L. (IT) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048239-A1 | Therapeutic compounds | RRP1B, RCE1, CTSZ | PRKCA 4250/4885MMP12 2067/4885GPR84 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.