SCHEMBL4210045

SCHEMBL4210045

CC1=Cc2ccsc2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.43
PTPRC P08575 1/20 0.36
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
USP2 O75604 2/20 0.33
GAA P10253 2/20 0.33
MAPK1 P28482 2/20 0.33
BLM P54132 2/20 0.33
PLIN1 O60240 1/20 0.33
NR1I2 O75469 1/20 0.33
GSR P00390 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CYP2D6 P10635 1/20 0.33
HSPD1 P10809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29915354 0.62 CES1 (0.71) CES1PTPRCPTGS2PABPC1DNMT1
SCHEMBL9673279 0.61 CES1 (0.89) CES1PTPRCLMNACYP1A2CYP3A4
SCHEMBL2111492 0.61 CES1 (0.70) CES1PTPRCMEN1KMT2ACDC25B
SCHEMBL206335 0.61 CES1 (0.79) CES1PTPRCPTGS2PABPC1DNMT1
SCHEMBL30448645 0.61 CES1 (1.00) CES1PTPRCLMNACYP1A2CYP3A4
SCHEMBL8303228 0.61
SCHEMBL2618057 0.60 CES1 (0.47) CES1PTPRCMEN1ALDH1A1KMT2A
SCHEMBL722595 0.59 CYP2A6 (0.56) CES1MEN1ALDH1A1MAPTKMT2A
SCHEMBL678100 0.59 MAPT (0.61) CES1PTPRCMEN1ALDH1A1MAPT
SCHEMBL6995084 0.59 CES1 (0.75) CES1PTPRCMEN1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090227748-A1 Process for Preparing Olff in Polymers in the Presence of Catalyst Systems Having Photochromic Groups BASELL POLYOLEFINE GMBH (DE) 2009-09-10 US disclosed
EP-1937700-A2 PROCESS FOR PREPARING OLEFIN POLYMERS IN THE PRESENCE OF CATALYST SYSTEMS HAVING PHOTOCHROMIC GROUPS Basell Polyolefine GmbH (DE) 2008-07-02 EP disclosed
WO-2007028536-A2 PROCESS FOR PREPARING OLEFIN POLYMERS IN THE PRESENCE OF CATALYST SYSTEMS HAVING PHOTOCHROMIC GROUPS BASELL POLYOLEFINE GMBH (DE) 2007-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227748-A1 Process for Preparing Olff in Polymers in the Presence of Catalyst Systems Having Photochromic Groups RTF1, POF1B, RTF2 CES1 4735/4885PTPRC 2124/4885MEN1 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.