SCHEMBL678100

SCHEMBL678100

CC1=Cc2ccccc2C1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.61
ALDH1A1 P00352 8/20 0.61
CDC25B P30305 7/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
CDC25A P30304 6/20 0.61
LMNA P02545 6/20 0.61
HPGD P15428 5/20 0.61
BLM P54132 5/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
TP53 P04637 5/20 0.61
MAPK1 P28482 4/20 0.61
CYP1A2 P05177 4/20 0.61
CYP3A4 P08684 4/20 0.61
IDO1 P14902 3/20 0.61
CYP2C9 P11712 3/20 0.61
CYP2C19 P33261 3/20 0.61
PKM P14618 2/20 0.61
HSPD1 P10809 2/20 0.61
HSPE1 P61604 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30715504 0.93 CDC25B (0.57) MAPTALDH1A1CDC25BMEN1KMT2A
SCHEMBL8773107 0.93 CDC25B (0.57) MAPTALDH1A1CDC25BMEN1KMT2A
Formic Acid SCHEMBL31606783 0.90 MAPT (0.52) MAPTALDH1A1CDC25BMEN1KMT2A
SCHEMBL7270394 0.79
SCHEMBL19415819 0.79 MAPT (0.61) MAPTALDH1A1CDC25BMEN1KMT2A
SCHEMBL395231 0.77 MEN1 (0.47) MAPTALDH1A1CDC25BMEN1KMT2A
SCHEMBL7146635 0.76 CDC25B (0.68) MAPTALDH1A1CDC25BMEN1KMT2A
Menadione SCHEMBL25970 0.76 MAPT (1.00) MAPTALDH1A1CDC25BMEN1KMT2A
Menadione SCHEMBL1364028 0.76 MAPT (1.00) MAPTALDH1A1CDC25BMEN1KMT2A
Menadione SCHEMBL19356853 0.76 MAPT (1.00) MAPTALDH1A1CDC25BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124878-B Manufacturing method of rubber rain shoes with chameleon effect 杭州星发彩印有限公司 2023-08-22 CN claimed
CN-113355028-A Light-cured material, display panel and preparation method thereof 深圳市华星光电半导体显示技术有限公司 2021-09-07 CN claimed
CN-104710256-B Cheap and efficient synthesis method of alpha-hydroxyketone compound 北京大学 2017-03-22 CN claimed
CN-104710256-A Cheap and efficient synthesis method of alpha-hydroxyketone compound UNIV BEIJING 2015-06-17 CN claimed
CN-114685703-B Catalyst compositions comprising fluorided supports and methods of use thereof 埃克森美孚化学专利公司 2026-05-12 CN disclosed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
US-12269793-B2 Affinity illudofulvene conjugates AF CHEMICALS, LLC (US) 2025-04-08 US disclosed
CN-119306612-A Preparation method of trans-aminoindan 中国科学院大连化学物理研究所 2025-01-14 CN disclosed
CN-116143602-B Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof 西南大学 2024-10-22 CN disclosed
CN-117551023-A Preparation method and application of N-thio-phenyl phthalimide compound 太原理工大学 2024-02-13 CN disclosed
CN-115124878-B Manufacturing method of rubber rain shoes with chameleon effect 杭州星发彩印有限公司 2023-08-22 CN disclosed
CN-116554104-A Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof 西南大学 2023-08-08 CN disclosed
WO-2004034963-A2 METHODS AND COMPOSITIONS USING CHOLINESTERASE INHIBITORS EISAI CO., LTD. (JP) 2004-04-29 WO disclosed
WO-2003092606-A2 CHOLINESTERASE INHIBITORS TO PREVENT INJURIES CAUSED BY CHEMICALS EISAI CO., LTD. (JP) 2003-11-13 WO disclosed
WO-2003024456-A1 METHODS FOR TREATING AND PREVENTING MIGRAINES EISAI CO., LTD. (JP) 2003-03-27 WO disclosed
US-6268444-B1 TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION DOW CHEMICAL COMPANY 2001-07-31 US disclosed
EP-0789680-A1 PROCESS FOR PREPARING CYCLIC KETONES HOECHST CELANESE CORPORATION (US) 1997-08-20 EP disclosed
WO-1996014284-A1 PROCESS FOR PREPARING CYCLIC KETONES HOECHST CELANESE CORPORATION (US) 1996-05-17 WO disclosed
US-5489712-A METHYLENATING SUBSTITUTED KETONE TO FORM ALPHA, BETA UNSATURATED KETONE, CYCLIZING IN PRESENCE OF ACID OR BASE HOECHST CELANESE CORPORATION (US) 1996-02-06 US disclosed
US-3976634-A ANTIINFLAMMATORY SANDOZ, INC. (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 MAPT 2405/4885ALDH1A1 4400/4885CDC25B 3373/4885
US-12269793-B2 Affinity illudofulvene conjugates OGFR, TNFSF11, FCER2 MAPT 2405/4885ALDH1A1 4400/4885CDC25B 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.