Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CCND1 | P24385 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SOD1 | P00441 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179235 | 0.93 | CDK4 (0.36) | CDK4CCND1TDP1 | |
| SCHEMBL6426597 | 0.91 | CDK4 (0.38) | CDK4CCND1 | |
| SCHEMBL3632871 | 0.86 | BCHE (0.34) | CDK4CCND1TDP1CYP2A6ALOX12 | |
| SCHEMBL11801475 | 0.77 | HEXA (0.42) | — | |
| SCHEMBL29351222 | 0.75 | CYP2A6 (0.37) | CDK4CCND1TDP1CYP2A6ALOX12 | |
| SCHEMBL9385329 | 0.74 | CDK4 (0.38) | CDK4CCND1 | |
| SCHEMBL377726 | 0.71 | CDK4 (0.33) | CDK4CCND1CYP2A6ALOX12 | |
| SCHEMBL7004471 | 0.71 | HTR2A (0.38) | CDK4CCND1CYP2A6ALOX12 | |
| SCHEMBL608395 | 0.71 | LMNA (0.49) | — | |
| SCHEMBL7365093 | 0.71 | FABP4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |