SCHEMBL421106

SCHEMBL421106

Cc1ccccc1COc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.58
GAA P10253 2/20 0.53
PKM P14618 1/20 0.53
MMP1 P03956 9/20 0.47
ADAM17 P78536 8/20 0.47
FFAR1 O14842 2/20 0.47
MMP13 P45452 4/20 0.47
ADAMTS4 O75173 1/20 0.47
ELANE P08246 1/20 0.47
KDM4E B2RXH2 1/20 0.46
S1PR1 P21453 1/20 0.46
S1PR5 Q9H228 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51691 0.89 GAA (0.56) MAOBGAAPKMMMP1MMP13
SCHEMBL10865258 0.87 MAOB (0.68) MAOBGAAFFAR1KDM4ES1PR1
SCHEMBL7754066 0.84 PKM (0.54) GAAPKMFFAR1ELANENPSR1
SCHEMBL419556 0.78 LMNA (0.73) MAOBGAAPKMMMP1ADAM17
SCHEMBL10894645 0.76 PKM (0.56) GAAPKMMMP1MMP13ELANE
SCHEMBL417833 0.76 GAA (0.65) MAOBGAAPKMELANENPSR1
SCHEMBL6280745 0.76 GAA (0.59) GAAPKMMMP1ADAM17ELANE
SCHEMBL51564 0.76 GAA (0.59) GAAPKMMMP1ADAM17ELANE
SCHEMBL420238 0.76 MAOB (0.56) MAOBGAAPKMELANE
SCHEMBL10452980 0.76 MAOB (0.65) MAOBGAAADAM17FFAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US claimed
EP-0997315-A1 Polycyclic phenol compounds and heat-sensitive recording materials employing them Nicca Chemical Co., Ltd. (JP) 2000-05-03 EP claimed
CN-114872471-B High-transparency thermosensitive recording material and preparation method thereof 广东冠豪新材料研发有限公司 2024-07-16 CN disclosed
US-12030328-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2024-07-09 US disclosed
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
EP-4227107-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-08-16 EP disclosed
US-20230147446-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-05-11 US disclosed
EP-4126557-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-02-08 EP disclosed
US-20220153052-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2022-05-19 US disclosed
EP-3941756-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2022-01-26 EP disclosed
US-11046043-B2 Linerless thermosensitive recording body package RICOH COMPANY, LTD. (JP) 2021-06-29 US disclosed
US-20070184978-A1 Thermosensitive recording material and method of producing the same RICOH COMPANY, LTD. (JP) 2007-08-09 US disclosed
EP-1816003-A1 Thermosensitive recording material and method for producing the same Ricoh Company, Ltd. (JP) 2007-08-08 EP disclosed
US-20060216537-A1 Coating paper which can be removed by water and a method for preparation thereof NIPPON PAPER PAPYLIA CO., LTD. (JP) 2006-09-28 US disclosed
EP-1705288-A2 A coating paper which can be removed by water and a method for preparation thereof Nippon Paper Industries Co., Ltd. (JP) 2006-09-27 EP disclosed
EP-0997315-A1 Polycyclic phenol compounds and heat-sensitive recording materials employing them Nicca Chemical Co., Ltd. (JP) 2000-05-03 EP disclosed
US-5102693-A Calendering intermediate layer to smooth surface, coating onto support and forming a thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1992-04-07 US disclosed
US-4975408-A INTERMEDIATE INSULATING LAYER HAVING SURFACE SMOOTHNESS GIVING IMPROVED COLORING SENSITIVITY; FOAMED LAYER HAVING MINUTE VOIDS RICOH COMPANY, LTD. (JP) 1990-12-04 US disclosed
US-4912079-A Thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1990-03-27 US disclosed
US-4895828-A INTERMEDIATE EXPANDED PLASTIC FILLER LAYER AND ELECTROCONDUCTIVE MATERIAL RICOH COMPANY, LTD. (JP) 1990-01-23 US disclosed