SCHEMBL51564

SCHEMBL51564

O=S(=O)(c1ccc(O)cc1)c1ccc(OCc2ccc(COc3ccc(S(=O)(=O)c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
APP P05067 2/20 0.59
PKM P14618 1/20 0.59
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC6A2 P23975 1/20 0.58
CYP2C19 P33261 1/20 0.58
PTGS2 P35354 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HIF1A Q16665 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
PTPRZ1 P23471 1/20 0.57
CA12 O43570 4/20 0.54
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
CA7 P43166 4/20 0.54
CA9 Q16790 4/20 0.54
ALDH1A1 P00352 1/20 0.53
CA4 P22748 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280745 1.00 GAA (0.59) GAAAPPPKMLMNACYP1A2
SCHEMBL420238 0.92 MAOB (0.56) GAAAPPPKMLMNACYP1A2
SCHEMBL7753235 0.92 PKM (0.75) GAAAPPPKMPTPRZ1ALDH1A1
SCHEMBL416484 0.92 NR4A2 (0.56) GAAAPPPKMLMNACYP1A2
SCHEMBL419556 0.91 LMNA (0.73) GAAPKMLMNACYP1A2PTGS1
SCHEMBL10709540 0.88 RXRA (0.59) GAAAPPPKMLMNACYP1A2
SCHEMBL11009256 0.87 LMNA (0.67) GAAPKMLMNACYP1A2PTGS1
SCHEMBL51406 0.86 LMNA (0.56) GAAPKMLMNACYP1A2PTGS1
SCHEMBL1793666 0.85 PKM (0.63) GAAPKMLMNACYP1A2PTGS1
SCHEMBL1793890 0.85 PKM (0.63) GAAPKMLMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475095-B1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH CO LTD (JP) 2020-01-22 EP disclosed
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH COMPANY, LTD. (JP) 2019-05-23 US disclosed
EP-3475095-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2019-05-01 EP disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
US-8563468-B2 Color developing composition containing molecular compound, and recording material NIPPON SODA CO., LTD. (JP) 2013-10-22 US disclosed
US-8497227-B2 Diphenylsulfone bridged compound, color forming substance for thermal recording and thermal recording material NICCA CHEMICAL CO., LTD. (JP) 2013-07-30 US disclosed
EP-2332733-B1 COLOR DEVELOPING COMPOSITION CONTAINING MOLECULAR COMPOUND, AND RECORDING MATERIAL NIPPON SODA CO (JP) 2012-11-28 EP disclosed
US-8283286-B2 Thermosensitive recording material NICCA CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
EP-2181854-B1 THERMOSENSITIVE RECORDING MATERIAL NICCA CHEMICAL CO (JP) 2012-08-15 EP disclosed
US-20030186810-A1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. 2003-10-02 US disclosed
US-6579828-B1 Plural color developing layer which develops different color tones by different heating conditions of thermal head. NIPPON PAPER INDUSTRIES CO. LTD (JP) 2003-06-17 US disclosed
EP-0999072-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2003-05-02 EP disclosed
EP-1273570-A1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO., LTD. (JP) 2003-01-08 EP disclosed
US-6407036-B1 MIXTURE OF FATTY AMIDE AND DIPHENYL SULFONE COMPOUND NIPPON PAPER INDUSTRIES CO. LTD (JP) 2002-06-18 US disclosed
US-6303540-B1 CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-10-16 US disclosed
EP-1092552-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-1092553-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-0999072-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-10 EP disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE CACNA1S, NCS1, TRPA1 GAA 3682/4885APP 2592/4885PKM 1477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.