SCHEMBL4211075

SCHEMBL4211075

CC=Cc1ccc(C)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.50
TP53 P04637 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 4/20 0.42
ALOX15 P16050 3/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 4/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
CNR2 P34972 1/20 0.41
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX5 P09917 2/20 0.39
PTGS1 P23219 2/20 0.39
HTT P42858 1/20 0.39
PTGS2 P35354 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10604117 1.00 TRPA1 (0.50) TRPA1TP53TDP1MAPTALOX15
SCHEMBL10190857 0.89 TRPA1 (0.56) TRPA1TP53TDP1MAPTALOX15
SCHEMBL1109599 0.83 MAPT (0.52) TRPA1TP53TDP1MAPTALOX15
SCHEMBL8829593 0.83 MAPT (0.52) TRPA1TP53TDP1MAPTALOX15
SCHEMBL7746080 0.83 MAPT (0.52) TRPA1TP53TDP1MAPTALOX15
SCHEMBL3850086 0.81 TRPA1 (0.48) TRPA1TP53TDP1MAPTALOX15
SCHEMBL3850081 0.81 TRPA1 (0.48) TRPA1TP53TDP1MAPTALOX15
SCHEMBL68762 0.80 TYR (0.59) ALOX5PTGS1CYP1A1CYP1B1SYNJ2
SCHEMBL68761 0.80 TYR (0.59) ALOX5PTGS1CYP1A1CYP1B1SYNJ2
SCHEMBL9743148 0.80 TYR (0.59) ALOX5PTGS1CYP1A1CYP1B1SYNJ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822592-B2 Aqueous emulsion polymer as dispersant BASF SE (DE) 2014-09-02 US disclosed
US-20090234062-A1 Aqueous emulsion polymer as dispersant CIBA SPECIALTY CHEMICALS CORP. 2009-09-17 US disclosed
EP-1444302-B1 LEVELLING AGENT AND ANTI-CRATERING AGENT CIBA HOLDING INC (CH) 2009-06-17 EP disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
EP-1562696-B1 AQUEOUS EMULSION POLYMER AS DISPERSANT CIBA SC HOLDING AG (CH) 2006-03-29 EP disclosed
US-20040236007-A1 Levelling agent and anti-cratering agent CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-25 US disclosed
EP-0307752-B1 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AG (DE) 1995-02-22 EP disclosed
US-5274174-A Process for the production of poly(4-hydroxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274173-A Process for the production of poly(4-acetoxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274175-A Process for the preparation of 4-acetoxyphenylmethyl carbinol HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
EP-0355983-A1 A process for the low residence time dehydration of p-acetoxyphenyl methylcarbinol HOECHST CELANESE CORPORATION (US) 1990-02-28 EP disclosed
EP-0353898-A1 Neat (solventless) hydrogenation of 4-acetoxyacetophenone in the production of 4-acetoxystyrene and its polymers and hydrolysis products HOECHST CELANESE CORPORATION (US) 1990-02-07 EP disclosed
EP-0353339-A2 A process for the production of poly(3-mono or 3,5-disubstituted-4-Acetoxystryrenes), their copolymers and hydrolysis thereof HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-07 EP disclosed
US-4868257-A Process for the production of 3-mono or 3,5 disubstituted-4-acetoxystyrene, its polymerization HOECHST CELANESE CORPORATION (US) 1989-09-19 US disclosed
EP-0104863-B1 LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307752-A2 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed
EP-0307751-A2 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed
US-4720345-A Semipermeable membranes of modified styrene-based polymers, process for their manufacture and their use ALIGENA AG (CH) 1988-01-19 US disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed