Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746080 | 1.00 | MAPT (0.52) | MAPTKDM4ELMNAHTTTRPA1 | |
| SCHEMBL1109599 | 1.00 | MAPT (0.52) | MAPTKDM4ELMNAHTTTRPA1 | |
| SCHEMBL4211075 | 0.83 | TRPA1 (0.50) | MAPTKDM4ELMNAHTTTRPA1 | |
| SCHEMBL10604117 | 0.83 | TRPA1 (0.50) | MAPTKDM4ELMNAHTTTRPA1 | |
| SCHEMBL3949848 | 0.80 | ALOX5 (0.57) | CNR2ALOX5TYRESR1ESR2 | |
| SCHEMBL3949851 | 0.80 | ALOX5 (0.57) | CNR2ALOX5TYRESR1ESR2 | |
| SCHEMBL69993 | 0.80 | ALDH1A1 (0.55) | MAPTKDM4ETP53TDP1CNR2 | |
| SCHEMBL69994 | 0.80 | ALDH1A1 (0.55) | MAPTKDM4ETP53TDP1CNR2 | |
| SCHEMBL6557065 | 0.78 | CNR2 (0.67) | MAPTKDM4ELMNATP53TDP1 | |
| SCHEMBL10497061 | 0.78 | ALOX5 (0.55) | CNR2ALOX5ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9059320-A | — | — | None | — | — | JP | disclosed |
| EP-2078003-B1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2007087128-A2 | SALT-SENSITIVE BINDERS FOR NONWOVEN WEBS AND METHOD OF MAKING SAME | CELANESE INTERNATIONAL CORPORATION (US) | 2007-08-02 | — | — | WO | disclosed |
| US-20070173594-A1 | Salt-sensitive binders for nonwoven webs and method of making same | CELANESE INTERNATIONAL CORPORATION | 2007-07-26 | — | — | US | disclosed |
| JP-H0959320-A | CURABLE COMPOSITION | DAI ICHI KOGYO SEIYAKU CO LTD | 1997-03-04 | — | — | JP | disclosed |
| US-4005158-A | O-(2-vinylphenyl)-thiol-phosphates | CIBA-GEIGY CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-3969442-A | O-(2-Vinylphenyl)-thiolphosphates | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
| US-3968223-A | Control of insects and acarids with O-(2-vinylphenyl)-thiolphosphates | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |