SCHEMBL68761

SCHEMBL68761

C/C=C/c1ccc(O)cc1O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.59
TTR P02766 2/20 0.59
SYNJ2 O15056 1/20 0.59
CYP1A1 P04798 1/20 0.59
BCHE P06276 1/20 0.59
MMP2 P08253 1/20 0.59
ALOX5 P09917 1/20 0.59
PTPN1 P18031 1/20 0.59
PTGS1 P23219 1/20 0.59
CYP1B1 Q16678 1/20 0.59
PTPN22 Q9Y2R2 1/20 0.59
CHRNA7 P36544 7/20 0.52
BACE1 P56817 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743148 1.00 TYR (0.59) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL68762 1.00 TYR (0.59) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL1822012 0.85 TYR (0.75) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL1822010 0.85 TYR (0.75) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL24777632 0.84 TTR (0.46) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL69994 0.82 ALDH1A1 (0.55) ALOX5BACE1
SCHEMBL69993 0.82 ALDH1A1 (0.55) ALOX5BACE1
SCHEMBL3209275 0.81 TYR (0.52) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL4211075 0.80 TRPA1 (0.50) TYRTTRSYNJ2CYP1A1BCHE
SCHEMBL10604117 0.80 TRPA1 (0.50) TYRTTRSYNJ2CYP1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746364-B2 Enzymatic synthesis of kavalactones and flavokavains WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2023-09-05 US disclosed
US-11739354-B2 Enzymatic synthesis of kavalactones and flavokavains WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2023-08-29 US disclosed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP disclosed
US-20140079836-A1 METHODS AND COMPOSITIONS FOR ALTERING HEALTH, WELLBEING, AND LIFESPAN LifeSpan Extension, LLC 2014-03-20 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0104863-B1 LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TYR 134/4885TTR 3513/4885SYNJ2 4647/4885
US-20140079836-A1 METHODS AND COMPOSITIONS FOR ALTERING HEALTH, WELLBEING, AND LIFESPAN TELO2, UQCRC1, COX5B TYR 999/4885TTR 1914/4885SYNJ2 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.