SCHEMBL4211097

SCHEMBL4211097

Cc1ccc(Nc2cc(CCc3ccccc3)ccc2C(=O)O)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ MAPT P10636 2/20 0.49
▸ RXFP1 Q9HBX9 1/20 0.49
▸ ALDH1A1 P00352 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ PLK1 P53350 4/20 0.46
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ RECQL P46063 1/20 0.45
▸ BLM P54132 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ PLK3 Q9H4B4 1/20 0.45
▸ CLCN2 P51788 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4225414 0.88 KMT2A (0.51) MAPTALDH1A1LMNAALOX12MEN1
SCHEMBL4215380 0.85 AKR1C3 (0.56) GAAMEN1KMT2AHCAR2
SCHEMBL4222869 0.84 TDP1 (0.60) NPC1RAB9AMAPTALDH1A1L3MBTL1
SCHEMBL4210607 0.82 AKR1C3 (0.62) SMN1; SMN2NPC1RAB9AMAPTALDH1A1
SCHEMBL4225455 0.82 MEN1 (0.66) SMN1; SMN2MAPTALDH1A1LMNAALOX12
SCHEMBL4225606 0.80 MEN1 (0.54) SMN1; SMN2NPC1RAB9AMAPTRXFP1
SCHEMBL4223020 0.79 MEN1 (0.63) MAPTALDH1A1MEN1KMT2ARECQL
SCHEMBL4226633 0.79 CLCN2 (0.52) GAASMN1; SMN2RAB9AMAPTALDH1A1
SCHEMBL4215640 0.79 MEN1 (0.52) MEN1KMT2ARECQLBLMTDP1
SCHEMBL4221452 0.77 TDP1 (0.51) GAASMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8327467-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2012-12-11 — — US disclosed
EP-1860098-B1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-14 — — EP disclosed
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-23 — — US disclosed
EP-1860098-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-11-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP11, MMP3 GAA 3059/4885SMN1; SMN2 4308/4885NPC1 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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