Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731921 | 1.00 | HSD11B1 (0.64) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL3731922 | 1.00 | HSD11B1 (0.64) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL81379 | 0.94 | HSD11B1 (0.72) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL81378 | 0.94 | HSD11B1 (0.72) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL3476254 | 0.94 | HSD11B1 (0.72) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| Hydrochloric Acid SCHEMBL4823034 | 0.92 | HSD11B1 (0.69) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL15828340 | 0.92 | HSD11B1 (0.69) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| Hydrochloric Acid SCHEMBL27954233 | 0.92 | HSD11B1 (0.69) | HSD11B1HCAR2CA12AKR1B10CA1 | |
| SCHEMBL4946181 | 0.89 | HCAR2 (0.71) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL4946176 | 0.89 | HCAR2 (0.71) | HCAR2CA12AKR1B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |