SCHEMBL81379

SCHEMBL81379

O=C(O)C=Cc1ccc(F)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.72
HCAR2 Q8TDS4 2/20 0.65
CA12 O43570 2/20 0.65
AKR1B10 O60218 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA3 P07451 2/20 0.65
AKR1B1 P15121 2/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
DPP4 P27487 2/20 0.65
CA5A P35218 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CA5B Q9Y2D0 2/20 0.65
ESR1 P03372 1/20 0.65
PKM P14618 1/20 0.65
TYR P14679 1/20 0.65
ESR2 Q92731 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476254 1.00 HSD11B1 (0.72) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL81378 1.00 HSD11B1 (0.72) HSD11B1HCAR2CA12AKR1B10CA1
Hydrochloric Acid SCHEMBL27954233 0.98 HSD11B1 (0.69) HSD11B1HCAR2CA12AKR1B10CA1
Hydrochloric Acid SCHEMBL4823034 0.98 HSD11B1 (0.69) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL15828340 0.98 HSD11B1 (0.69) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL3731922 0.94 HSD11B1 (0.64) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL3731921 0.94 HSD11B1 (0.64) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL4212976 0.94 HSD11B1 (0.64) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL7913684 0.90 TNFRSF1A (0.65) HSD11B1HCAR2CA12AKR1B10CA1
SCHEMBL17188516 0.90 TNFRSF1A (0.65) HSD11B1HCAR2CA12AKR1B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US claimed
CN-119890437-B Solid-state lithium ion battery polymer electrolyte based on p-fluoro cinnamic acid 合肥工业大学 2025-06-17 CN claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-119890437-A Solid-state lithium ion battery polymer electrolyte based on p-fluoro cinnamic acid 合肥工业大学 2025-04-25 CN claimed
CN-117430125-B Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2025-03-21 CN claimed
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-119431432-A Andrographolide diester derivative, preparation method and application 西北农林科技大学 2025-02-14 CN claimed
CN-118754842-A Tryptophan derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2024-10-11 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1526584-A2 Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same Samsung Electronics Co., Ltd (KR) 2005-04-27 EP claimed
US-6602679-B2 Substrate of an oxidant, stabilizer and buffer with an extended shelf life is useful with enzyme based probes; detecting DNA fragments in DNA sequencing GIRI BRIJ (US) 2003-08-05 US claimed
US-20030130300-A1 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US claimed
US-20020132064-A1 Liquid crystal display device LG DISPLAY CO., LTD. (KR) 2002-09-19 US claimed
US-6399165-B1 PYRANOSE POLYMER WITH LIGHT SENSITIVE ELEMENTS AND SUBSTRATE LG. PHILIPS LCD CO., LTD. (KR) 2002-06-04 US claimed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US claimed
WO-2001055446-A1 NOVEL STABILIZED FORMULATIONS FOR CHEMILUMINESCENT ASSAYS GIRI BRIJ PAL (US) 2001-08-02 WO claimed
US-5824377-A POLYSILOXANE HAVING PENDANT CINNAMOYL GROUP LG ELECTRONICS INC. (KR) 1998-10-20 US claimed
US-5538823-A Liquid crystal device utilizing thermostable polymeric material GOLDSTAR CO., LTD. (KR) 1996-07-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 HSD11B1 3809/4885HCAR2 2828/4885CA12 891/4885
US-20030130300-A1 Respiratory system disorders; synergistic mixtures ADRB3, ADRB1, CHRM3 HSD11B1 25/4885HCAR2 1526/4885CA12 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.